Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

335 questions · 406 findings · 23 reviews

No studies found 93 · 22.9%GRADE not reported 166 · 40.9%Very low 66 · 16.3%Low 65 · 16%Moderate 14 · 3.4%High 2 · 0.5%

High-viscosity glass-ionomer ART restorations vs Conventional treatment using composite (with local anaesthetic)

Restoration failure (primary dentition) · Children with carious primary teeth

ART using H-GIC led to higher restoration failure (primary teeth) compared with conventional treatment using composite (with local anaesthetic); GRADE not reported.

1 finding from 1 review

High-viscosity glass-ionomer ART restorations vs Conventional treatment using composite (with local anaesthetic)

Pain (primary dentition) · Children with carious primary teeth

ART using H-GIC showed no clear difference in pain (primary dentition) compared with conventional treatment using composite (with local anaesthetic); GRADE not reported.

1 finding from 1 review

Cessation of water fluoridation (fluoride removed from the water supply) vs Continued fluoridated water

Early childhood caries experience (mean dmft) · People of all ages in a previously fluoridated community (Maupome 2001: children with generally low caries experience)

The review found no eligible studies for this question.

1 finding from 1 review
  • No evidence to determine the effect of the cessation of water fluoridation on caries in deciduous teeth. No included study reported change in dmft following cessation.
    0 studies
    No studies found

Cessation of water fluoridation (fluoride removed from the water supply) vs Continued fluoridated water

Dental caries in permanent teeth · People of all ages in a previously fluoridated community (Maupome 2001: children with generally low caries experience)
1 finding from 1 review
  • Water fluoridation for the prevention of dental caries 2015 · Cochrane All outcomes
    Follow-up 3 years
    Insufficient evidence to determine the effect of the cessation of water fluoridation on caries. One study (Maupome 2001), at high risk of bias, over 3 years found no increase in caries in the fluoride-ended group…
    1 study · 9249 participants
    Very low

Cessation of water fluoridation (fluoride removed from the water supply) vs Continued fluoridated water

Disparities in caries across socioeconomic status (SES) · People of all ages in a previously fluoridated community (Maupome 2001: children with generally low caries experience)

The review found no eligible studies for this question.

1 finding from 1 review

SDF (given at a particular frequency, concentration, or duration) vs SDF (given at a different frequency, concentration, or duration)

Caries arrest · Children and adults (with or without carious lesions)
1 finding from 1 review

Silver diamine fluoride (SDF) vs placebo or no treatment

Caries arrest · Children and adults (with or without carious lesions)

It is very uncertain whether silver diamine fluoride (SDF) changes caries arrest compared with placebo or no treatment (very low certainty).

3 findings from 1 review

Silver diamine fluoride (SDF) vs Sealants or resin infiltration

Secondary prevention of caries · Children and adults (with or without carious lesions)

Silver diamine fluoride (SDF) showed no clear difference in secondary prevention of caries compared with sealants or resin infiltration; GRADE not reported.

1 finding from 1 review

Silver diamine fluoride (SDF) vs Sealants or resin infiltration

Primary caries prevention · Children and adults (with or without carious lesions)

The review found no eligible studies for this question.

3 findings from 1 review

Silver diamine fluoride (SDF) vs placebo or no treatment

Secondary prevention of caries · Children and adults (with or without carious lesions)

The review found no eligible studies for this question.

3 findings from 1 review

Silver diamine fluoride (SDF) vs Fluoride varnish

Dental pain or sensitivity · Children and adults (with or without carious lesions)

It is very uncertain whether silver diamine fluoride (SDF) changes dental pain or sensitivity compared with fluoride varnish (very low certainty).

1 finding from 1 review

Silver diamine fluoride (SDF) vs Fluoride varnish

Primary caries prevention · Children and adults (with or without carious lesions)

It is very uncertain whether silver diamine fluoride (SDF) changes primary caries prevention compared with fluoride varnish (very low certainty).

3 findings from 1 review

Silver diamine fluoride (SDF) vs placebo or no treatment

Primary caries prevention · Children and adults (with or without carious lesions)

It is very uncertain whether silver diamine fluoride (SDF) changes primary caries prevention compared with placebo or no treatment (very low certainty).

3 findings from 1 review