Findings

What do systematic reviews say?

124 questions · 125 findings · 17 reviews · Headline outcomes only

No studies found 33 · 26.4%GRADE not reported 10 · 8%Very low 27 · 21.6%Low 19 · 15.2%Moderate 31 · 24.8%High 5 · 4%

Serious adverse events · children under 18 years of age with enteric fever

The review found no eligible studies for this question.

1 finding from 1 review

Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Clinical failure · children under 18 years of age with enteric fever

Ceftriaxone showed no clear difference in clinical failure compared with azithromycin (low certainty).

1 finding from 1 review

Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins 2022 · Cochrane Headline outcomes only
RR 0.42 [0.11, 1.57]
3 studies · 196 participants
Low

Microbiological failure · children under 18 years of age with enteric fever

It is very uncertain whether ceftriaxone changes microbiological failure compared with azithromycin (very low certainty).

1 finding from 1 review

Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins 2022 · Cochrane Headline outcomes only
RR 1.95 [0.36, 10.64]
3 studies · 196 participants
Very low

Microbiological cure · Pregnant women with a confirmed Chlamydia trachomatis infection

It is very uncertain whether amoxicillin changes microbiological cure compared with azithromycin (very low certainty).

1 finding from 1 review

Interventions for treating genital Chlamydia trachomatis infection in pregnancy 2017 · Cochrane Headline outcomes only
RR 0.89 [0.71, 1.12]
2 studies · 144 participants
Very low