Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

313 questions · 319 findings · 81 reviews

No studies found 97 · 30.4%GRADE not reported 20 · 6.3%Very low 98 · 30.7%Low 66 · 20.7%Moderate 32 · 10%High 6 · 1.9%

Lamotrigine vs lithium

Recurrence of any episodes at one year for clinical worsening with additional psychotropics (mood stabilizers, antidepressants, antipsychotics or benzodiazepines) · bipolar disorder

Lamotrigine showed no clear difference in recurrence of any episodes at one year for clinical worsening with… compared with lithium (moderate certainty).

1 finding from 1 review

Lamotrigine vs placebo

Recurrence of any episodes at one year for clinical worsening with additional psychotropics (mood stabilizers, antidepressants, antipsychotics or benzodiazepines) · bipolar disorder

Lamotrigine probably leads to lower recurrence of any episodes at one year for clinical worsening with… compared with placebo (moderate certainty).

1 finding from 1 review

PERPHENAZINE vs antipsychotics

Other adverse events: any serious adverse event ‐ short and long term · patients with schizophrenia

It is very uncertain whether PERPHENAZINE changes other adverse events: any serious adverse event ‐ short and long term compared with ANY ANTIPSYCHOTICS (very low certainty).

1 finding from 1 review

HALOPERIDOL vs first‐generation antipsychotics

Behaviour: Leaving the study early (short‐term) · patients with schizophrenia

Haloperidol showed no clear difference in leaving the study early due to any reason as a measure of overall… compared with first‐generation antipsychotics (low certainty).

1 finding from 1 review

HALOPERIDOL vs first‐generation antipsychotics

Leaving the study early ‐ medium term ‐ any reason · patients with schizophrenia

It is very uncertain whether haloperidol changes leaving the study early due to any reason as a measure of overall… compared with first‐generation antipsychotics (very low certainty).

1 finding from 1 review