Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

143 questions · 144 findings · 18 reviews · Headline outcomes only

No studies found 8 · 5.6%GRADE not reported 1 · 0.7%Very low 32 · 22.2%Low 65 · 45.1%Moderate 32 · 22.2%High 6 · 4.2%

Interleukin‐2 RA vs no induction

Post‐transplantation lymphoproliferative disorder Number of participants diagnosed with PTLD · heart transplant recipients

Interleukin‐2 RA showed no clear difference in post‐transplantation lymphoproliferative disorder Number of… compared with no induction (low certainty).

1 finding from 1 review

Intervention not reported

Acute rejection Acute rejection grade 3A or more verified by biopsy · heart transplant recipients

The intervention showed no clear difference in acute rejection Acute rejection grade 3A or more verified by biopsy (low certainty).

1 finding from 1 review

Intervention not reported

Infection Number of participants diagnosed with infection · heart transplant recipients

The intervention showed no clear difference in infection Number of participants diagnosed with infection (low certainty).

1 finding from 1 review

Intervention not reported

Cytomegalovirus infection Number of patients diagnosed with CMV infection · heart transplant recipients

The intervention showed no clear difference in cytomegalovirus infection Number of patients diagnosed with CMV… (low certainty).

1 finding from 1 review

Intervention not reported

Post‐transplantation lymphoproliferative disorder Number of participants diagnosed with PTLD · heart transplant recipients

The intervention showed no clear difference in post‐transplantation lymphoproliferative disorder Number of… (low certainty).

1 finding from 1 review

Intervention not reported

Cancer Number of participants diagnosed with cancer · heart transplant recipients

The intervention showed no clear difference in cancer Number of participants diagnosed with cancer (low certainty).

1 finding from 1 review