Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,454 questions · 3,562 findings · 816 reviews · Headline outcomes only

No studies found 538 · 15.1%GRADE not reported 239 · 6.7%Very low 933 · 26.2%Low 1,041 · 29.2%Moderate 612 · 17.2%High 199 · 5.6%

Surface‐modified vs standard catheter

Death from any cause at day 28 of · AKI patients receiving CKRT

It is very uncertain whether surface‐modified changes death from any cause at day 28 of compared with standard double‐lumen catheter with identical geometry and flow design (very low certainty).

1 finding from 1 review

More frequent (less than eight hours) vs less frequent (eight hours or greater) monitoring of gastric residual volume

Pneumonia · adults receiving EN via nasogastric or gastrostomy tube

It is very uncertain whether more frequent (less than eight hours) changes pneumonia (until discontinued or up to 28 days) compared with less frequent (eight hours or greater) monitoring of gastric… (very low certainty).

1 finding from 1 review

No monitoring vs frequent monitoring (12 hours or less) of gastric residual volume

Pneumonia · adults receiving EN via nasogastric or gastrostomy tube

It is very uncertain whether no monitoring changes pneumonia (until discontinued or up to 28 days) compared with frequent monitoring (12 hours or less) of gastric residual volume (very low certainty).

1 finding from 1 review

Higher threshold (500 mL per six hours or greater) vs lower threshold (less than 500 mL per six hours) at time of aspiration

Pneumonia · adults receiving EN via nasogastric or gastrostomy tube

It is very uncertain whether higher threshold (500 mL per six hours or greater) changes pneumonia (until discontinued or up to 28 days) compared with lower threshold (less than 500 mL per six hours) at time of aspiration (very low certainty).

1 finding from 1 review