Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,476 questions · 1,535 findings · 101 reviews

No studies found 233 · 15.2%GRADE not reported 332 · 21.6%Very low 209 · 13.6%Low 343 · 22.3%Moderate 279 · 18.2%High 139 · 9.1%

Intervention not reported

Local‐regional recurrence Radiology · patients with resectable thoracic esophageal cancer

The intervention showed no clear difference in local‐regional recurrence Radiology (moderate certainty).

1 finding from 1 review

Intervention not reported

Distant recurrence Radiology · patients with resectable thoracic esophageal cancer

The intervention showed no clear difference in distant recurrence Radiology (moderate certainty).

1 finding from 1 review

Intervention not reported

Any complication Clinical · patients with resectable thoracic esophageal cancer

The intervention showed no clear difference in any complication Clinical (moderate certainty).

1 finding from 1 review

Intervention not reported

Postoperative death Clinical · patients with resectable thoracic esophageal cancer

The intervention showed no clear difference in postoperative death Clinical (low certainty).

1 finding from 1 review

Intervention not reported

Anastomotic leaks Clinical/radiology · patients with resectable thoracic esophageal cancer

The intervention showed no clear difference in anastomotic leaks Clinical/radiology (moderate certainty).

1 finding from 1 review

Non‐platinum therapies vs platinum combination

Grade 3 or higher hematological toxicity for platinum therapies ‐ anemia · non‐small cell lung cancer in the elderly population

Non‐platinum therapies may leads to higher grade 3 or higher hematological toxicity for platinum therapies ‐… compared with platinum combination (low certainty).

1 finding from 1 review

Non‐platinum therapies vs platinum combination

Grade 3 or higher hematological toxicity for platinum therapies ‐ thrombocytopenia · non‐small cell lung cancer in the elderly population

Non‐platinum therapies may leads to higher grade 3 or higher hematological toxicity for platinum therapies ‐… compared with platinum combination (low certainty).

1 finding from 1 review

Non‐platinum therapies vs platinum combination

Grade 3 or higher Non‐Hematological Toxicity for Platinum‐based therapies ‐ Peripheral neuropathy · non‐small cell lung cancer in the elderly population

Non‐platinum therapies may leads to higher grade 3 or higher Non‐Hematological Toxicity for Platinum‐based… compared with platinum combination (low certainty).

1 finding from 1 review