Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,954 questions · 2,335 findings · 149 reviews · Oral Health

No studies found 436 · 18.7%GRADE not reported 1,370 · 58.7%Very low 254 · 10.9%Low 173 · 7.4%Moderate 80 · 3.4%High 22 · 0.9%

Perioperative infraorbital nerve block vs Intravenous analgesia

Time to feeding after surgery · Children up to 13 years of age, undergoing cleft lip repair surgery

Perioperative infraorbital nerve block may leads to lower time to feeding after surgery (in minutes) compared with intravenous analgesia (low certainty).

1 finding from 1 review

Oral appliance or functional orthopaedic appliance vs placebo or no treatment

Nocturnal symptom: nightmares (questionnaire) · Children with obstructive sleep apnoea (aged 15 years or younger)

Oral appliance or functional orthopaedic appliance showed no clear difference in nocturnal symptom: nightmares (questionnaire) compared with placebo or no treatment; GRADE not reported.

1 finding from 1 review

Educational intervention with information and practical components (theoretical oral health education plus practical skills training) for nursing staff and/or residents vs (Optimised) usual care

Adverse effects of the interventions · Nursing home residents (mean age 78.3 to 86.0 years; more than 66% women; 62.1% to 87.3% with dental prostheses)

The review found no eligible studies for this question.

1 finding from 1 review

Monitoring (any means of observation, supervision, keeping under review, measuring or testing at intervals) vs No monitoring

Adverse events: Clinically important specific adverse events · People with serious mental illness (all included participants had schizophrenia); majority aged 18 to 65 years per NIMH 1987, or with…

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Dental caries prevalence in primary teeth (cavitated lesions) · Children aged 5-6 years in Latin America and the Caribbean

In Brazil, pooled primary-teeth caries prevalence in 5-6 year-olds was 52% (95% CI 49-54%); certainty not graded.

1 finding from 1 review

Oral appliance or functional orthopaedic appliance vs placebo or no treatment

Tiredness · Children with obstructive sleep apnoea (aged 15 years or younger)

It is very uncertain whether oral appliance or functional orthopaedic appliance changes daytime symptom: tiredness (Brouillette questionnaire) compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Oral appliance or functional orthopaedic appliance vs placebo or no treatment

Nocturnal symptom: habitual snoring (questionnaire) · Children with obstructive sleep apnoea (aged 15 years or younger)

It is very uncertain whether oral appliance or functional orthopaedic appliance changes nocturnal symptom: habitual snoring (questionnaire) compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Intervention not reported

Dental caries prevalence in primary teeth (cavitated lesions) · Children aged 5-6 years in Latin America and the Caribbean

About 56% of 5-6 year-old children in Latin America and the Caribbean had dental caries in primary teeth (95% CI 52-59%); certainty not graded.

1 finding from 1 review

Perioperative infraorbital nerve block vs Infiltration of the incision (peri-incisional infiltration)

Pain measured by valid instruments (mean postoperative pain score) · Children up to 13 years of age, undergoing cleft lip repair surgery
1 finding from 1 review

Laser (Er:YAG, Er,Cr:YSGG, or Nd:YAG) vs Conventional mechanical caries removal (standard drill; handpiece with a bur)

Restoration survival · Children, adolescents and adults with caries in deciduous and permanent teeth (age 3.5 to 84 years)

It is very uncertain whether laser (Er:YAG, Er,Cr:YSGG, or Nd:YAG) changes durability of restoration compared with conventional mechanical caries removal (standard drill; handpiece… (very low certainty).

3 findings from 1 review

Oral appliance or functional orthopaedic appliance vs placebo or no treatment

Side effects / tolerability · Children with obstructive sleep apnoea (aged 15 years or younger)
1 finding from 1 review

Perioperative infraorbital nerve block vs Intravenous analgesia

Need for analgesic prescription for pain (supplemental analgesic requirements) · Children up to 13 years of age, undergoing cleft lip repair surgery

It is very uncertain whether perioperative infraorbital nerve block changes need for analgesic prescription for pain (supplemental analgesic… compared with intravenous analgesia (very low certainty).

1 finding from 1 review

Perioperative infraorbital nerve block vs Placebo (sham/placebo device)

Heart rate, respiratory rate, and blood pressure · Children up to 13 years of age, undergoing cleft lip repair surgery
1 finding from 1 review

Oral appliance or functional orthopaedic appliance vs placebo or no treatment

Daytime symptom: sleepiness (Brouillette questionnaire) · Children with obstructive sleep apnoea (aged 15 years or younger)

It is very uncertain whether oral appliance or functional orthopaedic appliance changes daytime symptom: sleepiness (Brouillette questionnaire) compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Monitoring (any means of observation, supervision, keeping under review, measuring or testing at intervals) vs No monitoring

Dental state: No clinically important change in plaque index · People with serious mental illness (all included participants had schizophrenia); majority aged 18 to 65 years per NIMH 1987, or with…

The review found no eligible studies for this question.

1 finding from 1 review

Motivational interview plus oral health education vs Oral health education

Leaving the study early · People with serious mental illness (all included participants had schizophrenia); majority aged 18 to 65 years per NIMH 1987, or with…

Motivational interview plus oral health education showed no clear difference in leaving the study early compared with oral health education (moderate certainty).

1 finding from 1 review

Laser (Er:YAG, Er,Cr:YSGG, or Nd:YAG) vs Conventional mechanical caries removal (standard drill; handpiece with a bur)

Operator preference/fatigue in operator · Children, adolescents and adults with caries in deciduous and permanent teeth (age 3.5 to 84 years)
1 finding from 1 review
  • One study (Evans 2000): 11 dental practitioners expressed a preference in 73 of 77 'dentist/patient encounters', significantly in favour of conventional drill rather than laser (P < 0.001); main difficulty with laser…
    1 study
    GRADE not reported

Laser (Er:YAG, Er,Cr:YSGG, or Nd:YAG) vs Conventional mechanical caries removal (standard drill; handpiece with a bur)

Caries removal (clinical) · Children, adolescents and adults with caries in deciduous and permanent teeth (age 3.5 to 84 years)

Laser (Er:YAG, Er,Cr:YSGG, or Nd:YAG) showed no clear difference in caries removal (clinical) compared with conventional mechanical caries removal (standard drill; handpiece… (low certainty).

1 finding from 1 review