Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,411 questions · 2,571 findings · 265 reviews

No studies found 543 · 21.1%GRADE not reported 169 · 6.6%Very low 676 · 26.3%Low 731 · 28.4%Moderate 399 · 15.5%High 53 · 2.1%

Multi‐domain interventions vs placebo or usual care

Cognitive decline · Older people living in the community
3 findings from 1 review

Casirivimab/imdevimab vs usual care

Clinical progression: IMV or death (≥ 7 WHO scale) · hospitalised individuals with COVID‐19 (moderate to severe disease)

Casirivimab/imdevimab showed no clear difference in clinical progression: need for IMV or death (WHO ≥ 7) compared with usual care alone (moderate certainty).

1 finding from 1 review