Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,550 questions · 1,617 findings · 161 reviews · Neonatal

No studies found 238 · 14.7%GRADE not reported 76 · 4.7%Very low 377 · 23.3%Low 567 · 35.1%Moderate 285 · 17.6%High 74 · 4.6%

Familiar odour (breast milk smell) vs usual care

Pain (PIPP) · neonates with mechanical ventilation

Familiar odour (breast milk smell) showed no clear difference in PIPP during endotracheal suctioning Range of scale 0 to 21. Lower… compared with standard care (low certainty).

1 finding from 1 review

Facilitated tucking / four‐handed care / gentle human touch vs usual care

Pain (PIPP) · neonates with mechanical ventilation

Facilitated tucking / four‐handed care / gentle human touch showed no clear difference in PIPP during endotracheal suctioning Range of scale 0 to 21. Lower… compared with standard care (moderate certainty).

1 finding from 1 review

Facilitated tucking / four‐handed care / gentle human touch vs usual care

Heart rate · neonates with mechanical ventilation

Facilitated tucking / four‐handed care / gentle human touch showed no clear difference in heart rate compared with standard care (low certainty).

1 finding from 1 review

Facilitated tucking / four‐handed care / gentle human touch vs usual care

SaO 2 during endotracheal suctioning · neonates with mechanical ventilation

Facilitated tucking / four‐handed care / gentle human touch showed no clear difference in saO 2 during endotracheal suctioning compared with standard care (low certainty).

1 finding from 1 review

Facilitated tucking / four‐handed care / gentle human touch vs usual care

SDB during endotracheal suctioning · neonates with mechanical ventilation

Facilitated tucking / four‐handed care / gentle human touch showed no clear difference in SDB during endotracheal suctioning compared with standard care (low certainty).

1 finding from 1 review