Pain resolution · children (4 to 18 years) with functional abdominal pain disorders
It is very uncertain whether probiotic changes complete resolution of pain (at study end, as reported by study… compared with placebo (very low certainty).
1 finding from 1 review
Severity of pain (at study end, using the Faces Pain Scale) · children (4 to 18 years) with functional abdominal pain disorders
It is very uncertain whether probiotic changes severity of pain (at study end, using the Faces Pain Scale) compared with placebo (very low certainty).
1 finding from 1 review
Pain frequency or change in pain frequency · children (4 to 18 years) with functional abdominal pain disorders
It is very uncertain whether probiotic changes frequency of pain (at study end, episodes per week) compared with placebo (very low certainty).
1 finding from 1 review
Withdrawals due to adverse events · children (4 to 18 years) with functional abdominal pain disorders
It is very uncertain whether probiotic changes withdrawals due to adverse events compared with placebo (very low certainty).
1 finding from 1 review
Serious adverse events · children (4 to 18 years) with functional abdominal pain disorders
1 finding from 1 review
Adverse events (any) · children (4 to 18 years) with functional abdominal pain disorders
It is very uncertain whether probiotic changes adverse events (any) compared with placebo (very low certainty).
1 finding from 1 review
Treatment success as defined by the authors · children (4 to 18 years) with functional abdominal pain disorders
Synbiotic may leads to higher treatment success (at study end, as reported by study authors) compared with placebo (low certainty).
1 finding from 1 review
Pain resolution · children (4 to 18 years) with functional abdominal pain disorders
Synbiotic showed no clear difference in complete resolution of pain (at study end, as reported by study… compared with placebo (low certainty).
1 finding from 1 review
Change from baseline in 6MWT (metres) · 90 people with LOPD
1 finding from 1 review
Infusion reactions · 13 people with LOPD
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Need for respiratory support · 13 people with LOPD
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Use of a walking aid / wheelchair · 13 people with LOPD
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
QoL · 13 people with LOPD
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Treatment‐related adverse events · 13 people with LOPD
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Change from baseline in 6MWT (metres) · 13 people with LOPD
1 finding from 1 review
no estimate extracted
1 study · 5 participants
Very low
FVC (% predicted) Change from baseline · 13 people with LOPD
1 finding from 1 review
no estimate extracted
1 study · 5 participants
Very low
Infusion reactions · 13 people with LOPD
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Need for respiratory support · 13 people with LOPD
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Use of a walking aid / wheelchair · 13 people with LOPD
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
FVC (% predicted) Change from baseline · 90 people with LOPD
1 finding from 1 review