Findings

What do systematic reviews say?

2,016 questions · 2,067 findings · 222 reviews · Headline outcomes only

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No studies found 471 · 22.8%GRADE not reported 108 · 5.2%Very low 570 · 27.6%Low 458 · 22.2%Moderate 363 · 17.6%High 97 · 4.7%

Topical quinolone vs intramuscular gentamicin

Health‐related quality of life · adults with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical quinolone vs intramuscular gentamicin

Ear pain (otalgia) or discomfort or local irritation · adults with CSOM

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Very low

Topical quinolone vs intramuscular gentamicin

Hearing · adults with CSOM

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Very low

Topical quinolone vs intramuscular gentamicin

Serious complications · adults with CSOM

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Very low

Topical quinolone vs intramuscular gentamicin

Suspected ototoxicity · adults with CSOM

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Very low

Topical quinolone vs oral amoxicillin‐clavulanic acid combination

Resolution of ear discharge ‐ measured at 1 to 2 weeks · adults with CSOM

It is very uncertain whether topical quinolone changes resolution of ear discharge ‐ 1 to 2 weeks compared with oral amoxicillin‐clavulanic acid combination (very low certainty).

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
RR 2.93 [1.5, 5.72]
1 study · 56 participants
Very low

Topical quinolone vs oral amoxicillin‐clavulanic acid combination

Resolution of ear discharge ‐ measured after 4 weeks · adults with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical quinolone vs oral amoxicillin‐clavulanic acid combination

Health‐related quality of life · adults with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical quinolone vs oral amoxicillin‐clavulanic acid combination

Ear pain (otalgia) or discomfort or local irritation · adults with CSOM

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 56 participants
Very low

Topical quinolone vs oral amoxicillin‐clavulanic acid combination

Hearing · adults with CSOM

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 56 participants
Very low

Topical quinolone vs quinolones

Resolution of ear discharge ‐ measured after 4 weeks · people (of any age) with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical quinolone vs oral amoxicillin‐clavulanic acid combination

Serious complications · adults with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical quinolone vs oral amoxicillin‐clavulanic acid combination

Suspected ototoxicity · adults with CSOM

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 56 participants
Very low

Topical quinolone vs quinolones

Health‐related quality of life · people (of any age) with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical quinolone vs quinolones

Ear pain (otalgia) or discomfort or local irritation · people (of any age) with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical quinolone vs quinolones

Hearing · people (of any age) with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical quinolone vs quinolones

Serious complications · people (of any age) with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical quinolone vs quinolones

Suspected ototoxicity · people (of any age) with CSOM

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 265 participants
Very low

Topical quinolone vs intramuscular gentamicin

Resolution of ear discharge ‐ measured at 1 to 2 weeks · adults with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical quinolone vs intramuscular gentamicin

Resolution of ear discharge ‐ measured after 4 weeks · adults with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found