Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,733 questions · 1,794 findings · 326 reviews · Headline outcomes only

No studies found 243 · 13.5%GRADE not reported 96 · 5.4%Very low 597 · 33.3%Low 506 · 28.2%Moderate 303 · 16.9%High 49 · 2.7%

Penile traction therapy vs no treatment (short‐term)

Treatment discontinuation · men with Peyronie's disease (diagnosis of disease: varying, penile curvature: at least 30 degrees)

It is very uncertain whether penile traction therapy changes discontinuation from treatment compared with no treatment (short‐term) (very low certainty).

1 finding from 1 review

Longer vs shorter duration of combination nicotine replacement therapy

Smoking cessation ‐ 16 weeks versus 8 weeks · people who smoke

It is very uncertain whether longer changes smoking cessation ‐ 16 weeks versus 8 weeks compared with shorter duration of combination nicotine replacement therapy (very low certainty).

1 finding from 1 review

Longer vs shorter duration of combination nicotine replacement therapy

SAEs · people who smoke

It is very uncertain whether longer changes overall SAEs ‐ 26 weeks versus 8 weeks compared with shorter duration of combination nicotine replacement therapy (very low certainty).

3 findings from 1 review

Duplex ultrasound plus pulse palpation and arterial pressure index (ABI or TBI) vs pulse palpation plus arterial pressure index (ABI or TBI) (short term)

Limb salvage · people who underwent a lower limb revascularisation

Duplex ultrasound plus pulse palpation and arterial pressure index… showed no clear difference in limb salvage rate compared with pulse palpation plus arterial pressure index (ABI or TBI) (short term) (low certainty).

1 finding from 1 review

Duplex ultrasound plus pulse palpation and arterial pressure index (ABI or TBI) vs pulse palpation plus arterial pressure index (ABI or TBI) (short term)

Secondary patency (24 months) · people who underwent a lower limb revascularisation

Duplex ultrasound plus pulse palpation and arterial pressure index… showed no clear difference in vessel or graft secondary patency compared with pulse palpation plus arterial pressure index (ABI or TBI) (short term) (low certainty).

1 finding from 1 review

Duplex ultrasound plus pulse palpation and arterial pressure index (ABI or TBI) vs pulse palpation plus arterial pressure index (ABI or TBI) (short term)

All‐cause mortality · people who underwent a lower limb revascularisation

Duplex ultrasound plus pulse palpation and arterial pressure index… showed no clear difference in all‐cause mortality compared with pulse palpation plus arterial pressure index (ABI or TBI) (short term) (low certainty).

1 finding from 1 review