Findings

What do systematic reviews say?

4,667 questions · 21,760 findings · 2,177 reviews

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No studies found 4,173 · 19.2%GRADE not reported 2,300 · 10.6%Very low 5,276 · 24.2%Low 5,764 · 26.5%Moderate 3,298 · 15.2%High 949 · 4.4%

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Intervention not reported

Breast cancer stage at the time of presentation: defined as the proportion of women with breast cancer diagnosed at early stage (stage 0, I, II) Time of outcome assessment: 3 years to 20 years Method of measurement: CBE · health workers

The intervention may leads to higher breast cancer stage at the time of presentation: defined as the… (low certainty).

1 finding from 1 review

Training health workers in clinical breast examination for early detection of breast cancer in low‐ and middle‐income… 2023 · Cochrane Headline outcomes only
RR 1.44 [1.01, 2.06]
3 studies · 593 participants
Low

Intervention not reported

Breast cancer stage at the time of presentation: defined as the proportion of women with breast cancer diagnosed at late stage (stage III, IV) Time of outcome assessment: 3 years to 20 years Method of measurement: CBE · health workers

The intervention may leads to lower breast cancer stage at the time of presentation: defined as the… (low certainty).

1 finding from 1 review

Training health workers in clinical breast examination for early detection of breast cancer in low‐ and middle‐income… 2023 · Cochrane Headline outcomes only
RR 0.58 [0.36, 0.94]
3 studies · 593 participants
Low

Intervention not reported

Accuracy of health worker‐performed CBE Time of outcome assessment: 2 years to 20 years Method of measurement: Sensitivity, specificity and positive predictive value · health workers

1 finding from 1 review

Training health workers in clinical breast examination for early detection of breast cancer in low‐ and middle‐income… 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 2 participants
Very low

Alglucosidase alfa plus albuterol vs alglucosidase alfa plus placebo

FVC (% predicted) Change from baseline · 13 people with LOPD

1 finding from 1 review

Enzyme replacement therapy for late‐onset Pompe disease 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 5 participants
Very low

Alglucosidase alfa vs placebo

FVC (% predicted) Change from baseline · 90 people with LOPD

1 finding from 1 review

Enzyme replacement therapy for late‐onset Pompe disease 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 90 participants
Moderate

VAL‐1221 vs alglucosidase alfa

FVC (% predicted) Change from baseline · adults with LOPD

The review found no eligible studies for this question.

1 finding from 1 review

Enzyme replacement therapy for late‐onset Pompe disease 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Cipaglucosidase plus miglustat vs alglucosidase alfa plus placebo

Change in FVC · adults with LOPD

1 finding from 1 review

Enzyme replacement therapy for late‐onset Pompe disease 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 133 participants
Moderate

Cipaglucosidase plus miglustat vs alglucosidase alfa plus placebo

Change in SNIP (% predicted) · adults with LOPD

1 finding from 1 review

Enzyme replacement therapy for late‐onset Pompe disease 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 121 participants
Low

Avalglucosidase alfa vs alglucosidase alfa

FVC (% predicted) Change from baseline · adults with LOPD

1 finding from 1 review

Enzyme replacement therapy for late‐onset Pompe disease 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 100 participants
Moderate

Alglucosidase alfa plus clenbuterol vs alglucosidase alfa plus placebo

FVC (% predicted) Change from baseline · 13 people with LOPD

1 finding from 1 review

Enzyme replacement therapy for late‐onset Pompe disease 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 11 participants
Very low

Telemedicine vs usual care

HRQoL: using EQ‐5D (range from 0 to 1; higher values indicate better quality of life

1 finding from 1 review

Interventions for people with type 2 diabetes mellitus fasting during Ramadan 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 85 participants
Very low

Culturally and literacy adapted self‐management programme vs written information on the same topic

Health outcome – Any depression Time point a: short‐term (immediately post‐intervention) Multiple measures used: PHQ‐9K (score · migrants

1 finding from 1 review

Interventions for improving health literacy in migrants 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 555 participants
Very low

Culturally and literacy adapted audio‐/visual education without personal feedback vs no health literacy intervention

Health literacy – (1) Depression literacy · migrants

1 finding from 1 review

Interventions for improving health literacy in migrants 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 202 participants
Moderate

Culturally and literacy adapted audio‐/visual education without personal feedback vs no health literacy intervention

Health outcome – Any depression Time point a: short‐term (immediately post‐intervention) Multiple measures used: PHQ‐9K (score · migrants

1 finding from 1 review

Interventions for improving health literacy in migrants 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 337 participants
Low

Culturally and literacy adapted audio‐/visual education without personal feedback vs no health literacy intervention

Self‐efficacy – Self‐efficacy to identify need for treatmentfor depression · migrants

1 finding from 1 review

Interventions for improving health literacy in migrants 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 133 participants
Low

Culturally and literacy adapted audio‐/visual education without personal feedback vs written information on the same topic

Health outcome – Depression · migrants

1 finding from 1 review

Interventions for improving health literacy in migrants 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 445 participants
Low

Culturally and literacy adapted medical instruction vs no health literacy intervention

Health literacy – Medication understanding Multiple measures used: Demonstration by means of correct dosage in dosing tray (0 to 5) Correct interpretation of label contents, 11 labels MUQ (score · migrants

1 finding from 1 review

Interventions for improving health literacy in migrants 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 478 participants
Low

Summary of findings table ‐ Cognitive rehabilitation vs inactive control

Mood: depression (participant self‐report) · people with mild‐to‐moderate dementia (at medium‐term follow‐up)

1 finding from 1 review

Cognitive rehabilitation for people with mild to moderate dementia 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 456 participants
Moderate

Summary of findings table ‐ Cognitive rehabilitation vs inactive control

Mood: depression (participant self‐report) · people with mild‐to‐moderate dementia (at the end of therapy)

1 finding from 1 review

Cognitive rehabilitation for people with mild to moderate dementia 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 502 participants
Very low

Psychosocial interventions vs inactive control

Depressive symptoms · survivors of sexual violence and abuse

1 finding from 1 review

Psychosocial interventions for survivors of rape and sexual assault experienced during adulthood 2023 · Cochrane Headline outcomes only
no estimate extracted
12 studies · 901 participants
Low