Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,695 questions · 4,979 findings · 433 reviews

No studies found 998 · 20%GRADE not reported 1,140 · 22.9%Very low 1,024 · 20.6%Low 1,029 · 20.7%Moderate 636 · 12.8%High 152 · 3.1%

Oral methotrexate vs placebo

Primary outcome: complete clinical response (malar/discoid rash) · patients with cutaneous disease in systemic lupus erythematosus

Oral methotrexate may leads to higher primary outcome: complete clinical response (malar/discoid rash) compared with placebo (low certainty).

1 finding from 1 review

Oral azithromycin vs control

Ocular chlamydia trachomatis infection · people (any age) with active trachoma

The review found no eligible studies for this question.

1 finding from 1 review
  • Antibiotics for trachoma 2019 · Cochrane Headline outcomes only
    no estimate extracted
    Studies not reported
    No studies found

Oral azithromycin vs control

Antibiotic resistance · people (any age) with active trachoma

Oral azithromycin led to lower antibiotic resistance Proportion of samples showing evidence of… compared with control; GRADE not reported.

1 finding from 1 review
  • Antibiotics for trachoma 2019 · Cochrane Headline outcomes only
    no estimate extracted
    4 studies · 1354 participants
    GRADE not reported

Oral azithromycin vs control

Active trachoma · people (any age) with active trachoma

The review found no eligible studies for this question.

1 finding from 1 review
  • Antibiotics for trachoma 2019 · Cochrane Headline outcomes only
    no estimate extracted
    Studies not reported
    No studies found