Hepatic encephalopathy · people with hepatic encephalopathy
Branched‐chain amino acids (BCAA) leads to lower hepatic encephalopathy Psychometric and clinical assessments compared with control (high certainty).
1 finding from 1 review
Mean overall withdrawal score (participant rated) · Adults or adolescents with opioid dependence
Buprenorphine showed no clear difference in mean overall withdrawal score, with various methods of assessment compared with alpha2‐adrenergic agonists (moderate certainty).
1 finding from 1 review
Adverse effects: 1. Sedation · psychosis‐induced aggression or agitation
Benzodiazepines may leads to lower tranquillisation or asleep: sedation ‐ medium term ‐ lorazepam vs… compared with antihistamines plus antipsychotics (low certainty).
1 finding from 1 review
Tranquillisation or asleep: sedation ‐ medium term ‐ midazolam vs haloperidol + promethazineNumber of participants sedated · psychosis‐induced aggression or agitation
Benzodiazepines may leads to higher tranquillisation or asleep: sedation ‐ medium term ‐ midazolam vs… compared with antihistamines plus antipsychotics (low certainty).
1 finding from 1 review
Smoking cessation · young people
It is very uncertain whether behavioural interventions changes interventions with multiple delivery methods vs control Smoking… compared with minimal control (very low certainty).
1 finding from 1 review
Bone metastases · women with early breast cancer
Bisphosphonates probably leads to lower bone metastases compared with placebo/observation (moderate certainty).
1 finding from 1 review
Sensitivity analysis, meta‐regression analysis, first part · palliative participants with esophageal and GE‐junction carcinoma or gastric carcinoma
It is very uncertain whether summary of findings table (sensitivity analysis): interventions… changes sensitivity analysis, meta‐regression analysis, first part compared with gastric carcinoma (very low certainty).
1 finding from 1 review
Sensitivity analysis, meta‐regression analysis, second part · palliative participants with esophageal and GE‐junction carcinoma or gastric carcinoma
Summary of findings table (sensitivity analysis): interventions… probably leads to lower sensitivity analysis, meta‐regression analysis, second part compared with gastric carcinoma (moderate certainty).
1 finding from 1 review
Maternal infectious morbidity (chorioamnionitis and/or endometritis) · women with prelabour rupture of membranes at term (37 weeks' gestation or later)
Planned early birth may leads to lower maternal infectious morbidity (chorioamnionitis and/or endometritis) compared with expectant management (low certainty).
1 finding from 1 review
Vertical cup‐disc ratio: the proportion of participants with asymmetrical vertical cup‐disc ratio greater than 0.3 at 4 years' · people with open‐angle glaucoma
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Stride symmetry · acquired brain injury
1 finding from 1 review
Women's views/acceptability of method · incomplete miscarriage
Misoprostol showed no clear difference in women's views/acceptability of method compared with surgery (moderate certainty).
1 finding from 1 review
Women's views/acceptability of method · incomplete miscarriage
1 finding from 1 review
Intervention not reported
Systolic blood pressure clinical digital sphygmomanometer · adults with or without hypertension
1 finding from 1 review
Intervention not reported
Diastolic blood pressure clinical digital sphygmomanometer · adults with or without hypertension
1 finding from 1 review
Menstrual regularity at 12 months Laser LOD vs harmonic scalpel N of participants: 34 (1 RCT) · Women with symptoms of PCOS
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Improvement in androgenic symptoms · Women with symptoms of PCOS
LOD showed no clear difference in improvement in androgenic symptoms at 6 months (hirsutism/acne) ‐… compared with medical interventions (low certainty).
1 finding from 1 review
OR 1 [0.42, 2.37]
Studies not reported
Low
Harms: GI Upset at 6 months ‐ LOD vs metformin + clomiphene N of participants: 332 (2 RCTs) Harms: OHSS rates at 6 months ‐ LOD vs gonadotrophins N of participants: 33 (1 RCT) · Women with symptoms of PCOS
LOD probably leads to lower harms: GI Upset at 6 months ‐ LOD vs metformin + clomiphene N of… compared with medical interventions (moderate certainty).
1 finding from 1 review
OR 0.05 [0.01, 0.36]
Studies not reported
Moderate
Intervention not reported
Carriage of NTHi Not meta‐analysed · adults (> 18 years of age) with either COPD or recurrent acute exacerbations of chronic bronchitis
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Intervention not reported
Antibiotic prescriptions (number of courses/person/year) **Corticosteroids not meta‐analysed · adults (> 18 years of age) with either COPD or recurrent acute exacerbations of chronic bronchitis
The intervention may leads to higher antibiotic prescriptions (number of courses/person/year)… (low certainty).
1 finding from 1 review