Resolution of symptoms post‐treatment (evaluable participants) · group A streptococcal pharyngitis
Carbacephem showed no clear difference in resolution of symptoms post‐treatment (evaluable participants) compared with penicillin (low certainty).
1 finding from 1 review
Relapse · group A streptococcal pharyngitis
Carbacephem showed no clear difference in incidence of relapse (evaluable participants) compared with penicillin (low certainty).
1 finding from 1 review
Adverse events (ITT analysis) · group A streptococcal pharyngitis
Carbacephem showed no clear difference in adverse events (ITT analysis) compared with penicillin (low certainty).
1 finding from 1 review
Resolution of symptoms post‐treatment (evaluable participants) · group A streptococcal pharyngitis
It is very uncertain whether cephalosporins changes resolution of symptoms post‐treatment (evaluable participants) compared with penicillin (very low certainty).
1 finding from 1 review
Relapse · group A streptococcal pharyngitis
Cephalosporins may leads to lower incidence of relapse (evaluable participants) compared with penicillin (low certainty).
1 finding from 1 review
Adverse events (ITT analysis) · group A streptococcal pharyngitis
It is very uncertain whether cephalosporins changes adverse events (ITT analysis) compared with penicillin (very low certainty).
1 finding from 1 review
Resolution of symptoms post‐treatment (ITT analysis) · group A streptococcal pharyngitis
Macrolides showed no clear difference in resolution of symptoms post‐treatment (ITT analysis) compared with penicillin (low certainty).
1 finding from 1 review
Resolution of symptoms post‐treatment (evaluable participants) · group A streptococcal pharyngitis
Macrolides showed no clear difference in resolution of symptoms post‐treatment (evaluable participants) compared with penicillin (low certainty).
1 finding from 1 review
Relapse · group A streptococcal pharyngitis
Macrolides showed no clear difference in incidence of relapse (evaluable participants) compared with penicillin (low certainty).
1 finding from 1 review
Adverse events (ITT analysis) · group A streptococcal pharyngitis
Macrolides showed no clear difference in adverse events (ITT analysis) compared with penicillin (low certainty).
1 finding from 1 review
Clinical cure · group A streptococcal pharyngitis
It is very uncertain whether azithromycin changes clinical cure (ITT analysis) compared with amoxicillin (very low certainty).
1 finding from 1 review
Time to resolution of acute illness · children with acute pneumonia
1 finding from 1 review
Number of days in hospital (duration of hospitalisation) · children with acute pneumonia
1 finding from 1 review
Mortality rate ( · children with acute pneumonia
Vitamin D showed no clear difference in mortality rate ( compared with placebo (low certainty).
1 finding from 1 review
Pulmonary exacerbations · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen
Summary of findings: colistimethate dry powder for inhalation… showed no clear difference in pulmonary exacerbations: number of pulmonary exacerbations compared with tobramycin (moderate certainty).
1 finding from 1 review
QoL · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen
1 finding from 1 review
Survival: number of deaths · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen
Summary of findings: colistimethate dry powder for inhalation… showed no clear difference in survival: number of deaths compared with tobramycin (low certainty).
1 finding from 1 review
Adverse events: number of treatment related adverse events · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen
Summary of findings: colistimethate dry powder for inhalation… may leads to higher adverse events: number of treatment related adverse events compared with tobramycin (low certainty).
1 finding from 1 review
FEV1 % predicted: absolute change from baseline · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen
1 finding from 1 review
FVC (% predicted) Change from baseline · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen
1 finding from 1 review