Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,262 questions · 2,405 findings · 248 reviews · Headline outcomes only

No studies found 507 · 21.1%GRADE not reported 93 · 3.9%Very low 657 · 27.3%Low 708 · 29.4%Moderate 387 · 16.1%High 53 · 2.2%

Ketogenic diet (KD) vs usual care

Seizure freedom · children (aged 1 to 18 years) with drug‐resistant epilepsy

It is very uncertain whether ketogenic diet (KD) changes seizure freedom (100% reduction in seizure frequency) compared with usual care (very low certainty).

1 finding from 1 review

Ketogenic diet (KD) vs usual care

Treatment withdrawal · adults (aged 16 years and over) with drug‐resistant epilepsy

It is very uncertain whether ketogenic diet (KD) changes treatment withdrawal compared with usual care (very low certainty).

1 finding from 1 review

Ketogenic diet (KD) vs usual care

Seizure freedom · adults (aged 16 years and over) with drug‐resistant epilepsy

It is very uncertain whether ketogenic diet (KD) changes seizure freedom compared with usual care (very low certainty).

1 finding from 1 review

Ketogenic diet (KD) vs usual care

50% or greater reduction in seizure frequency · adults (aged 16 years and over) with drug‐resistant epilepsy

It is very uncertain whether ketogenic diet (KD) changes 50% or greater reduction in seizure frequency compared with usual care (very low certainty).

1 finding from 1 review