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Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,520 questions · 1,575 findings · 175 reviews · Headline outcomes only

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No studies found 239 · 15.2%GRADE not reported 59 · 3.7%Very low 337 · 21.4%Low 406 · 25.8%Moderate 410 · 26%High 124 · 7.9%

Intervention not reported

Proportion of wounds completely healed at 24 weeks · people with pressure ulcers

It is very uncertain whether the intervention changes proportion of wounds completely healed at 24 weeks (very low certainty).

1 finding from 1 review

Intervention not reported

Non‐serious adverse events · people with pressure ulcers

The intervention may leads to higher non‐serious adverse events (low certainty).

1 finding from 1 review

Intervention not reported

Serious adverse events · people with pressure ulcers

It is very uncertain whether the intervention changes serious adverse events (very low certainty).

1 finding from 1 review

ICS dose reduction vs no change

Rate of exacerbations requiring systemic corticosteroids · adults with asthma

It is very uncertain whether ICS dose reduction changes exacerbation requiring OCS compared with no change (very low certainty).

2 findings from 1 review

ICS dose reduction vs no change

SAEs · adults with asthma

ICS dose reduction showed no clear difference in all‐cause SAEs compared with no change (low certainty).

2 findings from 1 review