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Evidence found and GRADE certainty

4,783 questions · 10,022 findings · 882 reviews

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No studies found 2,100 · 21%GRADE not reported 1,013 · 10.1%Very low 2,237 · 22.3%Low 2,514 · 25.1%Moderate 1,709 · 17.1%High 449 · 4.5%

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Radiotherapy combined with anti‐VEGF vs anti‐VEGF alone

Progression to visual loss (loss of 3 or more lines on logMAR chart) · people with neovascular AMD

Radiotherapy combined with anti‐VEGF probably leads to higher loss of 3 or more lines of best‐corrected visual acuity Measured… compared with anti‐VEGF alone (moderate certainty).

1 finding from 1 review

Radiotherapy combined with anti‐VEGF vs anti‐VEGF alone

Change in visual acuity (logMAR) ‐ 12 months (negative is better) · people with neovascular AMD

Radiotherapy combined with anti‐VEGF showed no clear difference in change in best corrected visual acuity (logMAR units) Measured using… compared with anti‐VEGF alone (low certainty).

1 finding from 1 review

Summary of findings table ‐ Contact immunotherapy (diphencyprone) + hair growth stimulants (minoxidil) vs contact immunotherapy (diphencyprone)

Short‐term hair regrowth ≥ 75% (between 12 and 26 weeks of · adults with alopecia areata

It is very uncertain whether summary of findings table ‐ Contact immunotherapy (diphencyprone) +… changes short‐term hair regrowth ≥ 75% (between 12 and 26 weeks of compared with contact immunotherapy (diphencyprone) (very low certainty).

1 finding from 1 review

Transurethral microwave thermotherapy vs sham

Retreatment Participants requiring additional procedures or surgery · men with lower urinary tract symptoms secondary to benign prostatic obstruction

Transurethral microwave thermotherapy may leads to lower retreatment Participants requiring additional procedures or surgery compared with sham treatment (low certainty).

1 finding from 1 review

Transurethral microwave thermotherapy vs transurethral resection of the prostate

Major adverse events · men with lower urinary tract symptoms secondary to benign prostatic obstruction

Transurethral microwave thermotherapy probably leads to lower major adverse events compared with transurethral resection of the prostate (moderate certainty).

1 finding from 1 review

Transurethral microwave thermotherapy vs transurethral resection of the prostate

Retreatment Participants requiring additional procedures or surgery · men with lower urinary tract symptoms secondary to benign prostatic obstruction

Transurethral microwave thermotherapy probably leads to higher retreatment Participants requiring additional procedures or surgery compared with transurethral resection of the prostate (moderate certainty).

1 finding from 1 review

Transurethral microwave thermotherapy vs transurethral resection of the prostate

Erectile function · men with lower urinary tract symptoms secondary to benign prostatic obstruction

Transurethral microwave thermotherapy showed no clear difference in erectile function (sexually‐active men only) compared with transurethral resection of the prostate (low certainty).

1 finding from 1 review

Transurethral microwave thermotherapy vs transurethral resection of the prostate

Ejaculatory function · men with lower urinary tract symptoms secondary to benign prostatic obstruction

Transurethral microwave thermotherapy may leads to lower ejaculatory function (sexually‐active men only) compared with transurethral resection of the prostate (low certainty).

1 finding from 1 review