Unplanned operations at 12 months · adults with open long bone fractures of the upper and lower limbs
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events ‐ superficial infection · adults with open long bone fractures of the upper and lower limbs
It is very uncertain whether timing of wound closure (immediate changes adverse events ‐ superficial infection compared with delayed) (very low certainty).
1 finding from 1 review
Return to work · adults with open long bone fractures of the upper and lower limbs
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
HRQoL at 6 or 12 months · adults with open long bone fractures; study in the review included only Gustilo II open tibia fractures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Deep surgical site infection at 30 days or 90 days, or time points reported by study authors · adults with open long bone fractures; study in the review included only Gustilo II open tibia fractures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Delayed or non‐union at time points reported by study authors · adults with open long bone fractures; study in the review included only Gustilo II open tibia fractures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Unplanned operations at 12 months · adults with open long bone fractures; study in the review included only Gustilo II open tibia fractures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Adverse events: superficial infection · adults with open long bone fractures; study in the review included only Gustilo II open tibia fractures
It is very uncertain whether the intervention changes adverse events: superficial infection (very low certainty).
1 finding from 1 review
Intervention not reported
Return to work by 12 months · adults with open long bone fractures; study in the review included only Gustilo II open tibia fractures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Limb function at 6 or 12 months · adults with open long bone fractures of the upper and lower limbs
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
HRQoL at 6 or 12 months · adults with open long bone fractures of the upper and lower limbs
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Overall mortality · adults receiving mechanical ventilation for at least 48 hours
Topical plus systemic prophylaxis leads to lower overall mortality compared with placebo or no treatment (high certainty).
1 finding from 1 review
Respiratory tract infections ‐ topical plus systemic prophylaxis versus systemic prophylaxis alone · adults receiving mechanical ventilation for at least 48 hours
Topical prophylaxis showed no clear difference in respiratory tract infections ‐ topical plus systemic prophylaxis… compared with no topical prophylaxis (low certainty).
1 finding from 1 review
Respiratory infections · adults receiving mechanical ventilation for at least 48 hours
Topical prophylaxis may leads to lower respiratory tract infections ‐ topical prophylaxis versus no… compared with no topical prophylaxis (low certainty).
2 findings from 1 review
Dropouts due to adverse events · adults receiving mechanical ventilation for at least 48 hours
It is very uncertain whether topical prophylaxis changes dropouts due to adverse events compared with no topical prophylaxis (very low certainty).
1 finding from 1 review
Gastrointestinal adverse events · adults receiving mechanical ventilation for at least 48 hours
Topical prophylaxis showed no clear difference in gastrointestinal adverse events compared with no topical prophylaxis (low certainty).
1 finding from 1 review
Allergic adverse events · adults receiving mechanical ventilation for at least 48 hours
It is very uncertain whether topical prophylaxis changes allergic adverse events compared with no topical prophylaxis (very low certainty).
1 finding from 1 review
Respiratory infections · adults receiving mechanical ventilation for at least 48 hours
Topical plus systemic prophylaxis probably leads to lower respiratory tract infections compared with placebo or no treatment (moderate certainty).
1 finding from 1 review
Dropouts due to adverse events · adults receiving mechanical ventilation for at least 48 hours
Topical plus systemic prophylaxis showed no clear difference in dropouts due to adverse events compared with placebo or no treatment (low certainty).
1 finding from 1 review
Gastrointestinal adverse events · adults receiving mechanical ventilation for at least 48 hours
Topical plus systemic prophylaxis showed no clear difference in gastrointestinal adverse events compared with placebo or no treatment (low certainty).
1 finding from 1 review