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Evidence found and GRADE certainty

2,661 questions · 2,751 findings · 453 reviews

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No studies found 593 · 21.6%GRADE not reported 277 · 10.1%Very low 538 · 19.6%Low 712 · 25.9%Moderate 516 · 18.8%High 115 · 4.2%

INTERMITTENT (EARLY‐BASED) vs MAINTENANCE THERAPY

Adverse effects: tardive dyskinesia: long term (+ 26 weeks) as defined in each study · patients with schizophrenia

INTERMITTENT (EARLY‐BASED) showed no clear difference in adverse effects: tardive dyskinesia: long term (+26 weeks) as… compared with MAINTENANCE THERAPY (low certainty).

1 finding from 1 review

ANY INTERMITTENT DRUG TECHNIQUE vs MAINTENANCE THERAPY

Global state: average score: long term (+ 26 weeks) Global Assessment Scale (GAS). Scale from: 0 to 100. · patients with schizophrenia
2 findings from 1 review

ANY INTERMITTENT DRUG TECHNIQUE vs MAINTENANCE THERAPY

Adverse effects: tardive dyskinesia: long term (+ 26 weeks) as defined in each study · patients with schizophrenia

It is very uncertain whether INTERMITTENT (DRUG HOLIDAY) changes adverse effects: tardive dyskinesia: long term (+ 26 weeks) as… compared with MAINTENANCE THERAPY (very low certainty).

2 findings from 1 review