Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,543 questions · 2,589 findings · 168 reviews · Schizophrenia

No studies found 601 · 23.2%GRADE not reported 446 · 17.2%Very low 721 · 27.8%Low 505 · 19.5%Moderate 274 · 10.6%High 42 · 1.6%

WENDAN DECOCTION PLUS LOW DOSE ANTIPSYCHOTIC vs STANDARD DOSE ANTIPSYCHOTICS

Global state: Clinically important change ‐ no improvement ‐ defined as PANSS < 50% reduction (short term) · patients with schizophrenia

WENDAN DECOCTION PLUS LOW DOSE ANTIPSYCHOTIC probably leads to lower global state: Clinically important change ‐ no improvement ‐ defined… compared with NORMAL DOSE ANTIPSYCHOTIC (moderate certainty).

1 finding from 1 review

WENDAN DECOCTION PLUS LOW DOSE ANTIPSYCHOTIC vs STANDARD DOSE ANTIPSYCHOTICS

Adverse effects: any observed extrapyramidal symptoms ‐ short term (up to 6 months) · patients with schizophrenia

WENDAN DECOCTION PLUS LOW DOSE ANTIPSYCHOTIC probably leads to lower adverse effects: Movement disorders ‐ Extra Pyramidal Symptoms… compared with NORMAL DOSE ANTIPSYCHOTIC (moderate certainty).

1 finding from 1 review

WENDAN DECOCTION vs antipsychotics

Global state: Clinically important change ‐ no improvement ‐ defined as PANSS < 50% reduction (short term) · patients with schizophrenia

WENDAN DECOCTION showed no clear difference in global state: Clinically important change ‐ no improvement ‐ defined… compared with ANTIPSYCHOTIC DRUG (moderate certainty).

1 finding from 1 review

Educational intervention with information and practical components (theoretical oral health education plus practical skills training) for nursing staff and/or residents vs usual care

Service use: Emergency medical/dental treatment · People with serious mental illness (all included participants had schizophrenia); majority aged 18 to 65 years per NIMH 1987, or with…

The review found no eligible studies for this question.

1 finding from 1 review

Monitoring (any means of observation, supervision, keeping under review, measuring or testing at intervals) vs No monitoring

Oral health: Not brushing teeth twice a day · People with serious mental illness (all included participants had schizophrenia); majority aged 18 to 65 years per NIMH 1987, or with…

The review found no eligible studies for this question.

1 finding from 1 review

Educational intervention with information and practical components (theoretical oral health education plus practical skills training) for nursing staff and/or residents vs usual care

Leaving the study early · People with serious mental illness (all included participants had schizophrenia); majority aged 18 to 65 years per NIMH 1987, or with…

Oral health education (advice and training) showed no clear difference in leaving the study early compared with standard care (oral health advice not specifically emphasised beyond… (moderate certainty).

1 finding from 1 review

Educational intervention with information and practical components (theoretical oral health education plus practical skills training) for nursing staff and/or residents vs usual care

Dental state: No clinically important change in plaque index · People with serious mental illness (all included participants had schizophrenia); majority aged 18 to 65 years per NIMH 1987, or with…

It is very uncertain whether oral health education (advice and training) changes dental state: No clinically important change in plaque index compared with standard care (oral health advice not specifically emphasised beyond… (very low certainty).

1 finding from 1 review

Educational intervention with information and practical components (theoretical oral health education plus practical skills training) for nursing staff and/or residents vs usual care

Oral health: Not brushing teeth twice a day · People with serious mental illness (all included participants had schizophrenia); majority aged 18 to 65 years per NIMH 1987, or with…

The review found no eligible studies for this question.

1 finding from 1 review