Findings

What do systematic reviews say?

2,359 questions · 2,491 findings · 249 reviews

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No studies found 696 · 27.9%GRADE not reported 213 · 8.6%Very low 611 · 24.5%Low 595 · 23.9%Moderate 315 · 12.6%High 61 · 2.4%

Music intervention plus standard care vs active intervention plus standard care

Motivation for treatment/change · people with substance use disorders

1 finding from 1 review

Music therapy for people with substance use disorders 2022 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 411 participants
Moderate

Music intervention plus standard care vs active intervention plus standard care

Motivation to stay sober/clean · people with substance use disorders

1 finding from 1 review

Music therapy for people with substance use disorders 2022 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 258 participants
Moderate

Music intervention plus standard care vs active intervention plus standard care

Retention in treatment · people with substance use disorders

The review found no eligible studies for this question.

1 finding from 1 review

Music therapy for people with substance use disorders 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Music intervention plus standard care vs active intervention plus standard care

Serious adverse events · people with substance use disorders

The review found no eligible studies for this question.

1 finding from 1 review

Music therapy for people with substance use disorders 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Music intervention plus standard care vs active intervention plus standard care

Psychological outcomes (depression) · people with substance use disorders

1 finding from 1 review

Music therapy for people with substance use disorders 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 110 participants
Moderate

Music intervention plus standard care vs active intervention plus standard care

Craving · people with substance use disorders

1 finding from 1 review

Music therapy for people with substance use disorders 2022 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 232 participants
Low

Adaptive servo ventilation (ASV) plus best supportive care vs best supportive care alone or inactive control

Central AHI

The review found no eligible studies for this question.

1 finding from 1 review

Non‐invasive positive pressure ventilation for central sleep apnoea in adults 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Adaptive servo ventilation (ASV) plus best supportive care vs best supportive care alone or inactive control

Cardiovascular mortality

Adaptive servo ventilation (ASV) plus best supportive care probably leads to higher cardiovascular mortality ‐ up to 80 months Number of participants:… compared with best supportive care alone or inactive control (moderate certainty).

1 finding from 1 review

Non‐invasive positive pressure ventilation for central sleep apnoea in adults 2022 · Cochrane Headline outcomes only
RR 1.25 [1.04, 1.49]
Studies not reported
Moderate

Adaptive servo ventilation (ASV) plus best supportive care vs best supportive care alone or inactive control

Serious adverse events

The review found no eligible studies for this question.

1 finding from 1 review

Non‐invasive positive pressure ventilation for central sleep apnoea in adults 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Adaptive servo ventilation (ASV) plus best supportive care vs best supportive care alone or inactive control

Quality of sleep

The review found no eligible studies for this question.

1 finding from 1 review

Non‐invasive positive pressure ventilation for central sleep apnoea in adults 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Adaptive servo ventilation (ASV) plus best supportive care vs best supportive care alone or inactive control

Quality of life ‐ after 48 months Number of participants: 1325(1 RCT)

1 finding from 1 review

Non‐invasive positive pressure ventilation for central sleep apnoea in adults 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Adaptive servo ventilation (ASV) plus best supportive care vs best supportive care alone or inactive control

AHI

1 finding from 1 review

Non‐invasive positive pressure ventilation for central sleep apnoea in adults 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Adaptive servo ventilation (ASV) plus best supportive care vs best supportive care alone or inactive control

All‐cause mortality ‐ up to 80 months Number of participants: 1355(2 RCTs)

Adaptive servo ventilation (ASV) plus best supportive care showed no clear difference in all‐cause mortality ‐ up to 80 months Number of participants: 1355(2… compared with best supportive care alone or inactive control (low certainty).

1 finding from 1 review

Non‐invasive positive pressure ventilation for central sleep apnoea in adults 2022 · Cochrane Headline outcomes only
RR 0.56 [0.06, 4.93]
Studies not reported
Low

Adaptive servo ventilation (ASV) plus best supportive care vs best supportive care alone or inactive control

Time to life‐saving cardiovascular intervention

The review found no eligible studies for this question.

1 finding from 1 review

Non‐invasive positive pressure ventilation for central sleep apnoea in adults 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Berotralstat vs placebo or active control

Mortality (during · children or adults with Types I or II HAE

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for the long‐term prevention of hereditary angioedema attacks 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Berotralstat vs placebo or active control

Serious adverse events (during · children or adults with Types I or II HAE

Berotralstat showed no clear difference in serious adverse events (during compared with placebo or active control (low certainty).

1 finding from 1 review

Interventions for the long‐term prevention of hereditary angioedema attacks 2022 · Cochrane Headline outcomes only
RR 0.77 [0.02, 24.03]
3 studies · 128 participants
Low

Berotralstat vs placebo or active control

Quality of lifeAngioedema Quality of Life scale (lower score is better)(during · children or adults with Types I or II HAE

1 finding from 1 review

Interventions for the long‐term prevention of hereditary angioedema attacks 2022 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 130 participants
Moderate

Berotralstat vs placebo or active control

Disability standardised mean difference (lower is better) (during · children or adults with Types I or II HAE

1 finding from 1 review

Interventions for the long‐term prevention of hereditary angioedema attacks 2022 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 50 participants
Low

Berotralstat vs placebo or active control

Adverse events(during · children or adults with Types I or II HAE

Berotralstat showed no clear difference in adverse events(during compared with placebo or active control (moderate certainty).

1 finding from 1 review

Interventions for the long‐term prevention of hereditary angioedema attacks 2022 · Cochrane Headline outcomes only
RR 1.03 [0.88, 1.22]
3 studies · 128 participants
Moderate

C1 esterase inhibitor vs placebo or active control

Risk of HAE attacks (during · children or adults with Types I or II HAE

C1 esterase inhibitor may leads to lower risk of HAE attacks (during compared with placebo or active control (low certainty).

1 finding from 1 review

Interventions for the long‐term prevention of hereditary angioedema attacks 2022 · Cochrane Headline outcomes only
RR 0.29 [0.16, 0.5]
1 study · 43 participants
Low