Findings

What do systematic reviews say?

4,410 questions · 8,901 findings · 1,091 reviews

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No studies found 1,687 · 19%GRADE not reported 1,469 · 16.5%Very low 1,969 · 22.1%Low 2,060 · 23.1%Moderate 1,302 · 14.6%High 414 · 4.7%

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Intervention not reported

Clinical pregnancy; type of antioxidant (natural conceptions and undergoing fertility treatments) ‐ Melatonin lower dose versus melatonin higher dose№ of participants: 140(2 RCTs) · women with subfertility

The intervention showed no clear difference in clinical pregnancy; type of antioxidant (natural conceptions and… (low certainty).

1 finding from 1 review

Antioxidants for female subfertility 2020 · Cochrane Headline outcomes only
OR 0.94 [0.41, 2.15]
Studies not reported
Low

Maintenance treatment with antipsychotic drugs vs placebo/no treatment

QoL · schizophrenia

1 finding from 1 review

Maintenance treatment with antipsychotic drugs for schizophrenia 2020 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 1573 participants
Low

Maintenance treatment with antipsychotic drugs vs placebo/no treatment

Social functioning · schizophrenia

1 finding from 1 review

Maintenance treatment with antipsychotic drugs for schizophrenia 2020 · Cochrane Headline outcomes only
no estimate extracted
15 studies · 3588 participants
Moderate

Intervention not reported

Foot alignmentPirani score. Scale from: 0 to 6. A lower score indicates better alignment · participants with CTEV at initial presentation

1 finding from 1 review

Interventions for congenital talipes equinovarus (clubfoot) 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 38 participants
Low

Intervention not reported

Foot alignment Pirani score. A lower score indicates better alignment. Scale from: 0 to 6. · participants with CTEV (type of case (i.e. whether initial presentation or relapsed) not specified)

1 finding from 1 review

Interventions for congenital talipes equinovarus (clubfoot) 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 40 participants
Low

Home (point‐of‐use) fortification of foods with multiple micronutrient powders vs placebo or no intervention

Anaemia · children aged 6 to 23 months

Home (point‐of‐use) fortification of foods with multiple… probably leads to lower anaemia (haemoglobin values lower than 110 g/L) compared with no intervention or placebo (moderate certainty).

1 finding from 1 review

Home fortification of foods with multiple micronutrient powders for health and nutrition in children under two years… 2020 · Cochrane Headline outcomes only
RR 0.82 [0.76, 0.9]
16 studies · 9927 participants
Moderate

Home (point‐of‐use) fortification of foods with multiple micronutrient powders vs an iron‐only supplement

Anaemia · children aged 6 to 23 months

Home (point‐of‐use) fortification of foods with multiple… showed no clear difference in anaemia (haemoglobin values lower than 110 g/L) compared with an iron‐only supplement (low certainty).

1 finding from 1 review

Home fortification of foods with multiple micronutrient powders for health and nutrition in children under two years… 2020 · Cochrane Headline outcomes only
RR 0.89 [0.58, 1.39]
1 study · 145 participants
Low

Oral progestogen (dienogest, desogestrel) vs goserelin acetate

Uterine fibroid‐related symptoms (duration of uterine bleeding, measured at 12 weeks; lower = better) · women with uterine fibroids

1 finding from 1 review

Progestogens or progestogen‐releasing intrauterine systems for uterine fibroids (other than preoperative medical… 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 14 participants
Very low

Oral progestogen (dienogest, desogestrel) vs goserelin acetate

Uterine fibroid‐related symptoms (abnormal uterine bleeding, measured at 12 weeks, with the pictorial blood assessment chart (PBAC); lower = better) · women with uterine fibroids

1 finding from 1 review

Progestogens or progestogen‐releasing intrauterine systems for uterine fibroids (other than preoperative medical… 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 14 participants
Very low

LNG‐IUS vs oral progestogen (norethisterone acetate)

Change in fibroid related symptoms · women with uterine fibroids

1 finding from 1 review

Progestogens or progestogen‐releasing intrauterine systems for uterine fibroids (other than preoperative medical… 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 48 participants
Very low

Acupuncture vs no treatment

Participant‐reported pain intensity VAS (0‐10, lower score = less pain) · pain management in labour

1 finding from 1 review

Acupuncture or acupressure for pain management during labour 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 163 participants
Very low

Acupressure vs sham control

Pain intensity (0‐10cm visual analogue scale) · pain management in labour

1 finding from 1 review

Acupuncture or acupressure for pain management during labour 2020 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 472 participants
Very low

Acupressure vs usual care

Participant‐reported pain intensity VAS (0‐10, lower score = less pain) · pain management in labour

1 finding from 1 review

Acupuncture or acupressure for pain management during labour 2020 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 620 participants
Very low

Anti‐VEGF vs steroids

Central retinal thickness μm (CRT) change at 1 year The aim of treatment is to reduce central retinal thickness so thinner is better. · people with BRVO

1 finding from 1 review

Anti‐vascular endothelial growth factor for macular oedema secondary to branch retinal vein occlusion 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 343 participants
Moderate

Anti‐VEGF vs sham

Mean central retinal thickness (CRT) change at 6 months in microns (lower value is better) · macular oedema secondary to branch retinal vein occlusion

1 finding from 1 review

Anti‐vascular endothelial growth factor for macular oedema secondary to branch retinal vein occlusion 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 281 participants
Moderate

Anti‐VEGF vs laser

Mean central retinal thickness (CRT) change at 6 months in microns (lower value is better) · people with BRVO

1 finding from 1 review

Anti‐vascular endothelial growth factor for macular oedema secondary to branch retinal vein occlusion 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 201 participants
Moderate

tDCS vs active control

Secondary outcome measure: lower extremity function at the end of · people with stroke

2 findings from 1 review

Transcranial direct current stimulation (tDCS) for improving activities of daily living, and physical and cognitive… 2020 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 66 participants
Moderate
Transcranial direct current stimulation (tDCS) for improving activities of daily living, and physical and cognitive… 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

tDCS vs placebo or control

Secondary outcome measure: lower extremity function at the end of · people with stroke

1 finding from 1 review

Transcranial direct current stimulation (tDCS) for improving activities of daily living, and physical and cognitive… 2020 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 204 participants
Moderate

Intervention not reported

PIPP (maximum score within 3 minutes following lancing) · Neonates

1 finding from 1 review

Paracetamol (acetaminophen) for prevention or treatment of pain in newborns 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 38 participants
Low

Intervention not reported

Stratum corneum hydration (SCH) (at baseline and day 56 ± 4) Hahnel 2017: measured at 56 ± 4 days in mid‐volar arm and lower leg in arbitrary units from 0 (no water) to 120 (on water) using the Corneometer CM 825 Gillis 2016: measured at 12 weeks ... · people 60 years of age and older

1 finding from 1 review

Hygiene and emollient interventions for maintaining skin integrity in older people in hospital and residential care… 2020 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 266 participants
Very low