Leflunomide vs methotrexate
Dialysis · adults with renal vasculitis for maintenance therapy
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Findings
What do systematic reviews say?
4,749 questions · 14,261 findings · 832 reviews
No studies found 3,655 · 25.6%GRADE not reported 2,111 · 14.8%Very low 3,646 · 25.6%Low 3,028 · 21.2%Moderate 1,501 · 10.5%High 320 · 2.2%
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Leflunomide vs methotrexate
Relapse · adults with renal vasculitis for maintenance therapy
Leflunomide showed no clear difference in relapse compared with methotrexate (low certainty).
1 finding from 1 review
- RR 0.5 [0.22, 1.11]1 study · 54 participantsLow
Leflunomide vs methotrexate
Serious adverse events* · adults with renal vasculitis for maintenance therapy
Leflunomide showed no clear difference in serious adverse events* compared with methotrexate (low certainty).
1 finding from 1 review
- RR 11.81 [0.69, 203.68]1 study · 54 participantsLow
Leflunomide vs methotrexate
Infection · adults with renal vasculitis for maintenance therapy
Leflunomide showed no clear difference in infection compared with methotrexate (low certainty).
1 finding from 1 review
- RR 1.17 [0.27, 106.88]1 study · 54 participantsLow
Combined trabeculotomy with trabeculectomy vs trabeculotomy
Mean intraocular pressure · children at or before five years of age with primary congenital glaucoma
1 finding from 1 review
- no estimate extracted2 studies · 88 participantsVery low
Combined trabeculotomy with trabeculectomy vs trabeculotomy
Proportion of participants with IOP≤ 21 mmHg, with or without ocular hypotensive medications 1 year · children at or before five years of age with primary congenital glaucoma
It is very uncertain whether combined trabeculotomy with trabeculectomy changes surgical success: proportion with postoperative IOP ≤ 21 mmHg with… compared with trabeculotomy (very low certainty).
1 finding from 1 review
- RR 1.01 [0.9, 1.14]3 studies · 102 participantsVery low
Combined trabeculotomy with trabeculectomy vs trabeculotomy
Adverse outcomes Up to 3 years · children at or before five years of age with primary congenital glaucoma
It is very uncertain whether combined trabeculotomy with trabeculectomy changes adverse outcomes Up to 3 years compared with trabeculotomy (very low certainty).
1 finding from 1 review
- RR 0.73 [0.1, 5.43]3 studies · 102 participantsVery low
Viscotrabeculotomy vs conventional trabeculotomy
Mean IOP ( · children at or before five years of age with primary congenital glaucoma
1 finding from 1 review
- no estimate extracted2 studies · 42 participantsVery low
Viscotrabeculotomy vs conventional trabeculotomy
Proportion with postoperative IOP ≤ 21 mmHg (surgical success) with or without glaucoma medications 6 months after surgery · children at or before five years of age with primary congenital glaucoma
It is very uncertain whether viscotrabeculotomy changes proportion with postoperative IOP ≤ 21 mmHg (surgical success) with… compared with conventional trabeculotomy (very low certainty).
1 finding from 1 review
- RR 1.11 [0.7, 1.78]1 study · 41 participantsVery low
Viscotrabeculotomy vs conventional trabeculotomy
Hyphema · children at or before five years of age with primary congenital glaucoma
Viscotrabeculotomy showed no clear difference in adverse outcomes—hyphema Up to 6 months after surgery compared with conventional trabeculotomy (low certainty).
1 finding from 1 review
- RR 1.33 [0.63, 2.83]2 studies · 57 participantsLow
Microcatheter‐assisted trabeculotomy vs conventional trabeculotomy
Mean IOP ( · children at or before five years of age with primary congenital glaucoma
1 finding from 1 review
- no estimate extracted2 studies · 99 participantsModerate
Microcatheter‐assisted trabeculotomy vs conventional trabeculotomy
Proportion of participants with IOP≤ 21 mmHg, with or without ocular hypotensive medications 1 year · children at or before five years of age with primary congenital glaucoma
Microcatheter‐assisted trabeculotomy probably leads to higher proportion with postoperative IOP ≤ 21 mmHg (surgical success) with… compared with conventional trabeculotomy (moderate certainty).
1 finding from 1 review
- RR 1.54 [1.2, 1.97]2 studies · 99 participantsModerate
Microcatheter‐assisted trabeculotomy vs conventional trabeculotomy
Hyphema · children at or before five years of age with primary congenital glaucoma
Microcatheter‐assisted trabeculotomy probably leads to higher adverse outcomes— hyphema Up to 1 year after surgery compared with conventional trabeculotomy (moderate certainty).
1 finding from 1 review
- RR 2.25 [1.25, 4.04]2 studies · 102 participantsModerate
CBT vs alternative interventions
Sexual attitudes and behaviour · young people (aged 10 to 18 years old) with harmful sexual behaviour
1 finding from 1 review
- Cognitive‐behavioural therapy (CBT) interventions for young people aged 10 to 18 with harmful sexual behaviour 2020 · Cochrane Headline outcomes onlyno estimate extracted1 study · 16 participantsVery low
CBT vs alternative interventions
Thinking patterns (no study reported data on this outcome) · young people (aged 10 to 18 years old) with harmful sexual behaviour
The review found no eligible studies for this question.
1 finding from 1 review
- Cognitive‐behavioural therapy (CBT) interventions for young people aged 10 to 18 with harmful sexual behaviour 2020 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
CBT vs alternative interventions
Victim empathy (no study reported data on this outcome) · young people (aged 10 to 18 years old) with harmful sexual behaviour
The review found no eligible studies for this question.
1 finding from 1 review
- Cognitive‐behavioural therapy (CBT) interventions for young people aged 10 to 18 with harmful sexual behaviour 2020 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
CBT vs alternative interventions
Social functioning · young people (aged 10 to 18 years old) with harmful sexual behaviour
The review found no eligible studies for this question.
1 finding from 1 review
- Cognitive‐behavioural therapy (CBT) interventions for young people aged 10 to 18 with harmful sexual behaviour 2020 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
CBT vs alternative interventions
Emotional self‐regulation and impulse control (no study reported data on this outcome) · young people (aged 10 to 18 years old) with harmful sexual behaviour
The review found no eligible studies for this question.
1 finding from 1 review
- Cognitive‐behavioural therapy (CBT) interventions for young people aged 10 to 18 with harmful sexual behaviour 2020 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
CBT vs alternative interventions
Adverse events None of the included studies evaluated adverse events · young people (aged 10 to 18 years old) with harmful sexual behaviour
The review found no eligible studies for this question.
1 finding from 1 review
- Cognitive‐behavioural therapy (CBT) interventions for young people aged 10 to 18 with harmful sexual behaviour 2020 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Intervention not reported
Intervention (no. of studies/participants) · Patients with RRMS Interventions: Azathioprine, daclizumab, fingolimod, glatiramer acetate, Immunoglobulins, interferon beta 1a ‐1b,…
The review found no eligible studies for this question.
1 finding from 1 review
- Immunomodulators and immunosuppressants for relapsing‐remitting multiple sclerosis: a network meta‐analysis 2024 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found