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Evidence found and GRADE certainty

2,543 questions · 2,589 findings · 168 reviews · Schizophrenia

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No studies found 601 · 23.2%GRADE not reported 446 · 17.2%Very low 721 · 27.8%Low 505 · 19.5%Moderate 274 · 10.6%High 42 · 1.6%

CHLORPROMAZINE vs Clotiapine

Adverse effects: incidence of serious adverse effects. Movement disorders ‐ dyskinesia ‐short‐term · patients with schizophrenia

It is very uncertain whether chlorpromazine changes adverse effects: incidence of serious adverse effects. Movement… compared with clotiapine (very low certainty).

1 finding from 1 review

CHLORPROMAZINE vs Clotiapine

Adverse effects: 1. Clinically significant extrapyramidal side effects (2‐10 weeks) vs. standard higher dose (> 7.5‐15 mg/day) · patients with schizophrenia

The review found no eligible studies for this question.

1 finding from 1 review

CHLORPROMAZINE vs Clotiapine

Leaving the study early · patients with schizophrenia

It is very uncertain whether chlorpromazine changes leaving the study early: for any reason compared with clotiapine (very low certainty).

1 finding from 1 review

Intervention not reported

Service utilisation: hospital admission (short term) · patients with schizophrenia

The intervention showed no clear difference in service utilisation: hospital admission (short term) (low certainty).

1 finding from 1 review

Intervention not reported

Global state: clinically important change in global state · patients with schizophrenia
1 finding from 1 review

Intervention not reported

Global state: relapse · patients with schizophrenia
1 finding from 1 review

Intervention not reported

Mental state: clinically important change in mental state · patients with schizophrenia
1 finding from 1 review

Intervention not reported

Adverse effect/event: clinically important extrapyramidal adverse events ‐ akathisia (medium term) · patients with schizophrenia

The intervention showed no clear difference in adverse effect/event: clinically important extrapyramidal adverse… (low certainty).

1 finding from 1 review

Intervention not reported

Adverse effect/event: death · patients with schizophrenia
1 finding from 1 review

Intervention not reported

Leaving the study early: any reason (medium term) · patients with schizophrenia

The intervention showed no clear difference in leaving the study early: any reason (medium term) (low certainty).

1 finding from 1 review

Yoga vs NON‐STANDARD CARE

Mental state‐ general Not improved to an important extent · patients with schizophrenia

YOGA showed no clear difference in mental state: clinically important change PANSS ‐ not improved compared with NON‐STANDARD CARE (low certainty).

1 finding from 1 review

Yoga vs NON‐STANDARD CARE

Social functioning: clinically important change SOFS ‐ overall, not improved · patients with schizophrenia

YOGA showed no clear difference in social functioning: clinically important change SOFS ‐ overall, not… compared with NON‐STANDARD CARE (low certainty).

1 finding from 1 review

Yoga vs NON‐STANDARD CARE

Behaviour: Leaving the study early (short‐term) · patients with schizophrenia

YOGA probably leads to lower leaving the study early: short term compared with NON‐STANDARD CARE (moderate certainty).

1 finding from 1 review