Isolation of other micro‐organisms from the respiratory tract: number of participants isolating other micro‐organisms within the 15‐month · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen
Intravenous ceftazidime with tobramycin leads to higher isolation of other micro‐organisms from the respiratory tract:… compared with oral ciprofloxacin (high certainty).
1 finding from 1 review
Adverse effects of antibiotics: participants experiencing cough · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen
It is very uncertain whether inhaled tobramycin (TNS) changes adverse effects of antibiotics: participants experiencing cough compared with placebo (very low certainty).
1 finding from 1 review
Adverse effects of antibiotics · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen
Intravenous ceftazidime with tobramycin probably leads to lower adverse effects of antibiotics: compared with oral ciprofloxacin (moderate certainty).
1 finding from 1 review
FEV1 % predicted · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen
1 finding from 1 review
Intervention not reported
Mean BCVA (logMAR) · people with proliferative diabetic retinopathy undergoing vitrectomy
The intervention showed no clear difference in mean BCVA (logMAR) (low certainty).
1 finding from 1 review
Intervention not reported
Early POVCH Â · people with proliferative diabetic retinopathy undergoing vitrectomy
The intervention probably leads to lower early POVCH Â (moderate certainty).
1 finding from 1 review
Intervention not reported
Late POVCH Â · people with proliferative diabetic retinopathy undergoing vitrectomy
The intervention leads to lower late POVCH Â (high certainty).
1 finding from 1 review
Intervention not reported
Revision surgery for POVCH · people with proliferative diabetic retinopathy undergoing vitrectomy
The intervention showed no clear difference in revision surgery for POVCH (moderate certainty).
1 finding from 1 review
Intervention not reported
Revision surgery for recurrent traction and/or RRD · people with proliferative diabetic retinopathy undergoing vitrectomy
The intervention showed no clear difference in revision surgery for recurrent traction and/or RRD (low certainty).
1 finding from 1 review
Intervention not reported
Intraoperative retinal breaks · people with proliferative diabetic retinopathy undergoing vitrectomy
The intervention leads to lower intraoperative retinal breaks (high certainty).
1 finding from 1 review
Intervention not reported
Silicone oil use · people with proliferative diabetic retinopathy undergoing vitrectomy
It is very uncertain whether the intervention changes silicone oil use (very low certainty).
1 finding from 1 review
Progression to visual loss (loss of 3 or more lines on logMAR chart) · proliferative diabetic retinopathy
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Visual acuity · proliferative diabetic retinopathy
1 finding from 1 review
Complete regression of new vessels (dichotomous outcome) · proliferative diabetic retinopathy
Anti‐vascular endothelial growth factor (anti‐VEGF) with or without… probably leads to higher complete regression of new vessels (dichotomous outcome) compared with PRP alone (moderate certainty).
1 finding from 1 review
Regression of new vessels (continuous outcome): mean area of fluorescein leakage (mm2) fluorescein angiography · proliferative diabetic retinopathy
1 finding from 1 review
Presence of vitreous haemorrhaged · proliferative diabetic retinopathy
Anti‐vascular endothelial growth factor (anti‐VEGF) with or without… probably leads to lower presence of vitreous haemorrhaged compared with PRP alone (moderate certainty).
1 finding from 1 review
Need for vitrectomy · proliferative diabetic retinopathy
Anti‐vascular endothelial growth factor (anti‐VEGF) with or without… may leads to lower need for vitrectomy compared with PRP alone (low certainty).
1 finding from 1 review
Quality of life (VFQ‐25 General health) · proliferative diabetic retinopathy
1 finding from 1 review
Adverse events · proliferative diabetic retinopathy
1 finding from 1 review
Intervention not reported
Overall survival (OS) ‐ Network (subnet 1) included 19 pairwise comparisons ‐ Median · people with a confirmed diagnosis of advanced renal cell carcinoma (combined risk groups) without previous systemic anticancer therapy
The intervention showed no clear difference in overall survival (OS) ‐ Network (subnet 1) included 19 pairwise… (moderate certainty).
1 finding from 1 review