Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,550 questions · 1,617 findings · 161 reviews · Neonatal

No studies found 238 · 14.7%GRADE not reported 76 · 4.7%Very low 377 · 23.3%Low 567 · 35.1%Moderate 285 · 17.6%High 74 · 4.6%

nHFV vs nIPPV following failure of initial non‐invasive respiratory support

Mortality before hospital discharge · ventilated preterm infants with failure of initial non‐invasive respiratory support

nHFV showed no clear difference in mortality before hospital discharge compared with nIPPV following failure of initial non‐invasive respiratory support (low certainty).

1 finding from 1 review

nHFV vs nIPPV following failure of initial non‐invasive respiratory support

Endotracheal intubation To discharge · ventilated preterm infants with failure of initial non‐invasive respiratory support

It is very uncertain whether nHFV changes endotracheal intubation To discharge compared with nIPPV following failure of initial non‐invasive respiratory support (very low certainty).

1 finding from 1 review