Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,587 questions · 5,761 findings · 495 reviews

No studies found 1,011 · 17.5%GRADE not reported 1,797 · 31.2%Very low 1,100 · 19.1%Low 1,052 · 18.3%Moderate 649 · 11.3%High 152 · 2.6%

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Juvenile idiopathic arthritis (JIA) vs Children and adolescents without JIA (healthy peers)

Oral health-related quality of life · Children and adolescents with juvenile idiopathic arthritis (JIA)

Evidence on OHRQoL was limited: one study found no significant difference between groups while another found orofacial symptoms affected daily life more in JIA; no pooled estimate (ungraded).

1 finding from 1 review

Juvenile idiopathic arthritis (JIA) vs Children and adolescents without JIA (healthy peers)

Plaque index (PI) / oral hygiene · Children and adolescents with juvenile idiopathic arthritis (JIA)

Evidence on oral hygiene/dental plaque was inconsistent: several studies found higher plaque in the JIA group while others found no difference; no pooled estimate (ungraded).

1 finding from 1 review

Secondary education vs University education

Prevalence of fair/poor self-rated oral health · Adults aged 25 years and older in Australia, Canada, New Zealand, and the United States

In United States, secondary versus university education differed by 27.5 percentage points in prevalence of fair/poor self-rated oral health.

4 findings from 1 review
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Primary education vs University education

Prevalence of fair/poor self-rated oral health · Adults aged 25 years and older in Australia, Canada, New Zealand, and the United States

In New Zealand, primary versus university education differed by 17.59 percentage points in prevalence of fair/poor self-rated oral health.

5 findings from 1 review
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Medium income vs High income

Prevalence of fair/poor self-rated oral health · Adults aged 25 years and older in Australia, Canada, New Zealand, and the United States

In Canada, medium versus high income differed by 8.3 percentage points in prevalence of fair/poor self-rated oral health.

4 findings from 1 review
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Post-secondary education vs University education

Prevalence of fair/poor self-rated oral health · Adults aged 25 years and older in Australia, Canada, New Zealand, and the United States

In Canada, post-secondary versus university education differed by 2.4 percentage points in prevalence of fair/poor self-rated oral health.

4 findings from 1 review
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Low income vs High income

Prevalence of fair/poor self-rated oral health · Adults aged 25 years and older in Australia, Canada, New Zealand, and the United States

Across four countries, low versus high income differed by 15.77 percentage points in prevalence of fair/poor self-rated oral health (random-effects meta-analysis; I2=13.4%).

5 findings from 1 review
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Oral propranolol vs placebo

Clearance, as assessed by a clinician at any · infantile haemangiomas (strawberry birthmarks) of the skin

Oral propranolol probably leads to higher clearance, as assessed by a clinician at any compared with placebo (moderate certainty).

1 finding from 1 review

Oral propranolol vs topical timolol

Adverse events experienced at short or long term ‐ general adverse events 24 weeks' · infantile haemangiomas (strawberry birthmarks) of the skin

It is very uncertain whether oral propranolol changes adverse events experienced at short or long term ‐ general adverse… compared with topical timolol (very low certainty).

1 finding from 1 review

Oral propranolol vs topical timolol

Other measures of resolution, as assessed by a clinician, at any · infantile haemangiomas (strawberry birthmarks) of the skin

Oral propranolol showed no clear difference in other measures of resolution, as assessed by a clinician, at any compared with topical timolol (low certainty).

1 finding from 1 review

Oral propranolol vs placebo

A subjective measure of improvement, as assessed by the parent or child, at any · infantile haemangiomas (strawberry birthmarks) of the skin

The review found no eligible studies for this question.

1 finding from 1 review

Oral propranolol vs placebo

Adverse events experienced at short or long term ‐ Serious adverse events 24 weeks' · infantile haemangiomas (strawberry birthmarks) of the skin

Oral propranolol showed no clear difference in adverse events experienced at short or long term ‐ Serious adverse… compared with placebo (low certainty).

1 finding from 1 review