Relapse · adults with renal vasculitis for maintenance therapy
Leflunomide showed no clear difference in relapse compared with methotrexate (low certainty).
1 finding from 1 review
Serious adverse events* · adults with renal vasculitis for maintenance therapy
Leflunomide showed no clear difference in serious adverse events* compared with methotrexate (low certainty).
1 finding from 1 review
Infection · adults with renal vasculitis for maintenance therapy
Leflunomide showed no clear difference in infection compared with methotrexate (low certainty).
1 finding from 1 review
Mean intraocular pressure · children at or before five years of age with primary congenital glaucoma
1 finding from 1 review
Proportion of participants with IOP≤ 21 mmHg, with or without ocular hypotensive medications 1 year · children at or before five years of age with primary congenital glaucoma
It is very uncertain whether combined trabeculotomy with trabeculectomy changes surgical success: proportion with postoperative IOP ≤ 21 mmHg with… compared with trabeculotomy (very low certainty).
1 finding from 1 review
Adverse outcomes Up to 3 years · children at or before five years of age with primary congenital glaucoma
It is very uncertain whether combined trabeculotomy with trabeculectomy changes adverse outcomes Up to 3 years compared with trabeculotomy (very low certainty).
1 finding from 1 review
Mean IOP ( · children at or before five years of age with primary congenital glaucoma
1 finding from 1 review
Proportion with postoperative IOP ≤ 21 mmHg (surgical success) with or without glaucoma medications 6 months after surgery · children at or before five years of age with primary congenital glaucoma
It is very uncertain whether viscotrabeculotomy changes proportion with postoperative IOP ≤ 21 mmHg (surgical success) with… compared with conventional trabeculotomy (very low certainty).
1 finding from 1 review
Hyphema · children at or before five years of age with primary congenital glaucoma
Viscotrabeculotomy showed no clear difference in adverse outcomes—hyphema Up to 6 months after surgery compared with conventional trabeculotomy (low certainty).
1 finding from 1 review
Mean IOP ( · children at or before five years of age with primary congenital glaucoma
1 finding from 1 review
Proportion of participants with IOP≤ 21 mmHg, with or without ocular hypotensive medications 1 year · children at or before five years of age with primary congenital glaucoma
Microcatheter‐assisted trabeculotomy probably leads to higher proportion with postoperative IOP ≤ 21 mmHg (surgical success) with… compared with conventional trabeculotomy (moderate certainty).
1 finding from 1 review
Hyphema · children at or before five years of age with primary congenital glaucoma
Microcatheter‐assisted trabeculotomy probably leads to higher adverse outcomes— hyphema Up to 1 year after surgery compared with conventional trabeculotomy (moderate certainty).
1 finding from 1 review
Sexual attitudes and behaviour · young people (aged 10 to 18 years old) with harmful sexual behaviour
1 finding from 1 review
Thinking patterns (no study reported data on this outcome) · young people (aged 10 to 18 years old) with harmful sexual behaviour
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Victim empathy (no study reported data on this outcome) · young people (aged 10 to 18 years old) with harmful sexual behaviour
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Social functioning · young people (aged 10 to 18 years old) with harmful sexual behaviour
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Emotional self‐regulation and impulse control (no study reported data on this outcome) · young people (aged 10 to 18 years old) with harmful sexual behaviour
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events None of the included studies evaluated adverse events · young people (aged 10 to 18 years old) with harmful sexual behaviour
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Talc poudrage (4 RCTs; 553 participants) · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin, IPC – not daily drainage, doxycycline, placebo Comparator…
1 finding from 1 review
Intervention not reported
Bleomycin (14 RCTs; 774 participants) · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin, IPC – not daily drainage, doxycycline, placebo Comparator…
1 finding from 1 review