Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,372 questions · 3,874 findings · 666 reviews

No studies found 431 · 11.1%GRADE not reported 783 · 20.2%Very low 995 · 25.7%Low 909 · 23.5%Moderate 596 · 15.4%High 160 · 4.1%

Community professional‐led interventions vs no care

Depression symptoms (1 to 6 months post intervention) Beck Depression Inventorye; Oxford Measure of Psychosocial Adjustmentd (higher score = higher severity) · children/adolescents with post‐traumatic stress and related depressive/anxiety symptoms
1 finding from 1 review

Lay health worker‐led psychosocial interventions vs enhanced usual care

Depression symptoms ‐ intermediate term (1 to 6 months post intervention) GHQ‐12a; PHQ‐9d,e,f; self‐reporting questionnaireh (higher score = higher severity) · women with perinatal depression
1 finding from 1 review

Lay health worker‐led psychosocial interventions vs enhanced usual care

Functional impairment · women with perinatal depression

Lay health worker‐led psychosocial interventions showed no clear difference in functional impairment ‐ intermediate term (1 to 6 months post… compared with enhanced usual care (low certainty).

1 finding from 1 review

Primary health professional‐led or collaborative care vs usual or enhanced care

Depressive symptoms · women with perinatal depression

It is very uncertain whether primary health professional‐led collaborative care interventions changes depression symptoms ‐ intermediate term (1 to 6 months post… compared with usual or enhanced care (very low certainty).

1 finding from 1 review

Primary health professional‐led or collaborative care vs usual or enhanced care

Quality of life ‐ intermediate term (1 to 6 months post intervention) SF‐36 social functioning (higher score = higher quality of life) · women with perinatal depression

It is very uncertain whether primary health professional‐led collaborative care interventions changes quality of life ‐ intermediate term (1 to 6 months post… compared with usual or enhanced care (very low certainty).

1 finding from 1 review

Lay health worker‐led psychological interventions vs usual care

Severity of CMD symptoms (including anxiety and depression) ‐ intermediate term (1 to 6 months post intervention) Measured by PHQ‐9a,d,f; SRQ‐20b (higher score, higher severity) · adults with common mental disorders
1 finding from 1 review

Lay health worker‐led psychological interventions vs usual care

PTS symptoms ‐ intermediate term (1 to 6 months post intervention) PCL‐5a,d,e; PCL‐6f; Post‐traumatic Stress Diagnostic Scaleb (higher score = higher severity) · adults with post‐traumatic stress and CMDs
1 finding from 1 review