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Evidence found and GRADE certainty

3,703 questions · 3,824 findings · 858 reviews

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No studies found 573 · 15%GRADE not reported 383 · 10%Very low 993 · 26%Low 1,062 · 27.8%Moderate 614 · 16.1%High 199 · 5.2%

Platelet‐rich plasma gel vs absorbent sterile cotton gauze

Time to complete healing · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease

Platelet‐rich plasma gel may leads to higher time to wound healing (days) compared with absorbent sterile cotton gauze (low certainty).

1 finding from 1 review

Gentamicin‐impregnated collagen sponge vs no dressing

Time to complete healing · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease

It is very uncertain whether gentamicin‐impregnated collagen sponge changes time to wound healing (days) compared with no dressing (very low certainty).

1 finding from 1 review

Dialkylcarbamoyl chloride (DACC)‐coated dressing vs alginate dressing

Proportion of wounds healed · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease

It is very uncertain whether dialkylcarbamoyl chloride (DACC)‐coated dressing changes proportion of wounds healed at 25 days compared with alginate dressing (very low certainty).

1 finding from 1 review

Zinc oxide mesh vs placebo mesh

Proportion of wounds healed · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease

It is very uncertain whether zinc oxide mesh changes proportion of wounds healed at 30 days compared with placebo mesh (very low certainty).

1 finding from 1 review

Duct‐to‐mucosa vs invagination pancreaticojejunostomy

Length of hospital stay · adults undergoing open pancreaticoduodenectomy

It is very uncertain whether duct‐to‐mucosa changes length of hospital stay (days) compared with invagination pancreaticojejunostomy (very low certainty).

1 finding from 1 review

Any intervention vs steroid alone or plus levofloxacin

Proportion of eyes in which SEI had developed within 21 days of treatment (lower is favored) · epidemic keratoconjunctivitis

It is very uncertain whether any intervention changes proportion of eyes in which SEI had developed within 21 days of… compared with steroid alone or plus levofloxacin (very low certainty).

1 finding from 1 review

Any intervention vs steroid alone or plus levofloxacin

Proportion of participants who discontinued medication and did not develop rebound SEI within 21 days (higher is favored) · epidemic keratoconjunctivitis

It is very uncertain whether any intervention changes proportion of participants who discontinued medication and did not… compared with steroid alone or plus levofloxacin (very low certainty).

1 finding from 1 review

Any intervention vs steroid alone or plus levofloxacin

Proportion of initially unaffected fellow eyes that had signs/symptoms of infection within 7 days of onset of signs/symptoms in the first eye (lower is favored) · epidemic keratoconjunctivitis

The review found no eligible studies for this question.

1 finding from 1 review