Findings

What do systematic reviews say?

2,209 questions · 2,322 findings · 227 reviews · Headline outcomes only

Sort:Best matchNewest Highest certainty Download CSV

No studies found 644 · 27.7%GRADE not reported 135 · 5.8%Very low 591 · 25.5%Low 582 · 25.1%Moderate 309 · 13.3%High 61 · 2.6%

Interventions (vitamin B1, mefenamic acid, tranexamic acid) vs placebo or active comparators (desmopressin, sodium diclofenac, flavonoids)

Side effects or other adverse events

The review found no eligible studies for this question.

1 finding from 1 review

Interventions to prevent or treat heavy menstrual bleeding or pain associated with intrauterine‐device use 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Interventions (vitamin B1, mefenamic acid, tranexamic acid) vs placebo or active comparators (desmopressin, sodium diclofenac, flavonoids)

Menstrual blood loss: mean loss

2 findings from 1 review

Interventions to prevent or treat heavy menstrual bleeding or pain associated with intrauterine‐device use 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 94 participants
Low
Interventions to prevent or treat heavy menstrual bleeding or pain associated with intrauterine‐device use 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 38 participants
Very low

Topical clonidine (TC) vs active comparators

Patient Global Impression of Change much or very much improved · adults with painful diabetic neuropathy

The review found no eligible studies for this question.

1 finding from 1 review

Topical clonidine for neuropathic pain in adults 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical clonidine (TC) vs active comparators

PGIC very much improved · adults with painful diabetic neuropathy

The review found no eligible studies for this question.

1 finding from 1 review

Topical clonidine for neuropathic pain in adults 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical clonidine (TC) vs active comparators

Withdrawals due to adverse events · adults with painful diabetic neuropathy

The review found no eligible studies for this question.

1 finding from 1 review

Topical clonidine for neuropathic pain in adults 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical clonidine (TC) vs active comparators

Number of participants reporting an adverse event · adults with painful diabetic neuropathy

The review found no eligible studies for this question.

1 finding from 1 review

Topical clonidine for neuropathic pain in adults 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical clonidine (TC) vs active comparators

Lack of efficacy withdrawal · adults with painful diabetic neuropathy

The review found no eligible studies for this question.

1 finding from 1 review

Topical clonidine for neuropathic pain in adults 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical clonidine (TC) vs active comparators

Participant‐reported pain relief of 50% or greater · adults with painful diabetic neuropathy

Topical clonidine (TC) showed no clear difference in participant‐reported pain relief of 50% or greater during longest compared with active comparator (low certainty).

1 finding from 1 review

Topical clonidine for neuropathic pain in adults 2022 · Cochrane Headline outcomes only
RR 1.41 [0.99, 2]
1 study · 139 participants
Low

Topical clonidine (TC) vs active comparators

Participant‐reported pain relief of 30% or greater · adults with painful diabetic neuropathy

The review found no eligible studies for this question.

1 finding from 1 review

Topical clonidine for neuropathic pain in adults 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Music intervention plus standard care vs active intervention plus standard care

Motivation for treatment/change · people with substance use disorders

1 finding from 1 review

Music therapy for people with substance use disorders 2022 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 411 participants
Moderate

Music intervention plus standard care vs active intervention plus standard care

Motivation to stay sober/clean · people with substance use disorders

1 finding from 1 review

Music therapy for people with substance use disorders 2022 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 258 participants
Moderate

Music intervention plus standard care vs active intervention plus standard care

Retention in treatment · people with substance use disorders

The review found no eligible studies for this question.

1 finding from 1 review

Music therapy for people with substance use disorders 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Music intervention plus standard care vs active intervention plus standard care

Serious adverse events · people with substance use disorders

The review found no eligible studies for this question.

1 finding from 1 review

Music therapy for people with substance use disorders 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Music intervention plus standard care vs active intervention plus standard care

Psychological outcomes (depression) · people with substance use disorders

1 finding from 1 review

Music therapy for people with substance use disorders 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 110 participants
Moderate

Music intervention plus standard care vs active intervention plus standard care

Craving · people with substance use disorders

1 finding from 1 review

Music therapy for people with substance use disorders 2022 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 232 participants
Low

Adaptive servo ventilation (ASV) plus best supportive care vs best supportive care alone or inactive control

Central AHI

The review found no eligible studies for this question.

1 finding from 1 review

Non‐invasive positive pressure ventilation for central sleep apnoea in adults 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Adaptive servo ventilation (ASV) plus best supportive care vs best supportive care alone or inactive control

Cardiovascular mortality

Adaptive servo ventilation (ASV) plus best supportive care probably leads to higher cardiovascular mortality ‐ up to 80 months Number of participants:… compared with best supportive care alone or inactive control (moderate certainty).

1 finding from 1 review

Non‐invasive positive pressure ventilation for central sleep apnoea in adults 2022 · Cochrane Headline outcomes only
RR 1.25 [1.04, 1.49]
Studies not reported
Moderate

Adaptive servo ventilation (ASV) plus best supportive care vs best supportive care alone or inactive control

Serious adverse events

The review found no eligible studies for this question.

1 finding from 1 review

Non‐invasive positive pressure ventilation for central sleep apnoea in adults 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Adaptive servo ventilation (ASV) plus best supportive care vs best supportive care alone or inactive control

Quality of sleep

The review found no eligible studies for this question.

1 finding from 1 review

Non‐invasive positive pressure ventilation for central sleep apnoea in adults 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Adaptive servo ventilation (ASV) plus best supportive care vs best supportive care alone or inactive control

Quality of life ‐ after 48 months Number of participants: 1325(1 RCT)

1 finding from 1 review

Non‐invasive positive pressure ventilation for central sleep apnoea in adults 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low