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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

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Intervention or exposure

Comparison

Outcome

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Review versions

515 questions in 31 reviews · Fertility Regulation

current versions

No studies 99 · 19.2%Ungraded 11 · 2.1%Very low 70 · 13.6%Low 147 · 28.5%Moderate 153 · 29.7%High 35 · 6.8%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Question	Effect	Evidence	Status / GRADE
Mid‐dose mifepristone (25 mg‐50 mg) vs levonorgestrel 1.5 mg Specific side effect ‐ vomiting · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	no estimate extracted	NR	No studies
Mid‐dose mifepristone (25 mg‐50 mg) vs levonorgestrel 1.5 mg Specific side effect ‐ spotting/bleeding after treatment · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	RR 0.61 [0.42, 0.88]	9 studies · 1796 participants	Low
Mid‐dose mifepristone (25 mg‐50 mg) vs levonorgestrel 1.5 mg Menses ‐ early · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	RR 0.72 [0.5, 1.03]	7 studies · 1324 participants	Low
Mid‐dose mifepristone (25 mg‐50 mg) vs levonorgestrel 1.5 mg Menses ‐ delay · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	RR 1.29 [1.09, 1.54]	17 studies · 3615 participants	Moderate
Low‐dose mifepristone (< 25 mg) vs levonorgestrel 1.5 mg Observed number of pregnancies (all women) · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	RR 0.72 [0.52, 0.99]	14 studies · 8752 participants	High
Low‐dose mifepristone (< 25 mg) vs levonorgestrel 1.5 mg Any side effect · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	RR 0.26 [0.17, 0.38]	3 studies · 609 participants	Low
Low‐dose mifepristone (< 25 mg) vs levonorgestrel 1.5 mg Specific side effect ‐ nausea · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	RR 0.95 [0.84, 1.09]	5 studies · 6384 participants	Moderate
Low‐dose mifepristone (< 25 mg) vs levonorgestrel 1.5 mg Specific side effect ‐ vomiting · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	RR 1.22 [0.55, 2.68]	3 studies · 6085 participants	Low
Low‐dose mifepristone (< 25 mg) vs levonorgestrel 1.5 mg Specific side effect ‐ spotting/bleeding after treatment · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	RR 0.61 [0.54, 0.69]	5 studies · 4598 participants	High
Levonorgestrel vs Yuzpe Any side effect · Women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	RR 0.8 [0.75, 0.86]	1 study · 1955 participants	High
Low‐dose mifepristone (< 25 mg) vs levonorgestrel 1.5 mg Menses ‐ early · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	RR 0.45 [0.35, 0.59]	5 studies · 1800 participants	Low
Low‐dose mifepristone (< 25 mg) vs levonorgestrel 1.5 mg Menses ‐ delay · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	RR 1.7 [1.48, 1.97]	9 studies · 7520 participants	Low
Mifepristone (all doses) vs Yuzpe Observed number of pregnancies (all women) · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	RR 0.14 [0.05, 0.41]	3 studies · 2144 participants	High
Mifepristone (all doses) vs Yuzpe Any side effect · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	RR 0.83 [0.77, 0.88]	2 studies · 1693 participants	Moderate
Mifepristone (all doses) vs Yuzpe Specific side effects ‐ nausea · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	RR 0.63 [0.53, 0.76]	3 studies · 2186 participants	Moderate
Mifepristone (all doses) vs Yuzpe Specific side effects ‐ vomiting · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	RR 0.12 [0.07, 0.2]	3 studies · 2186 participants	High
Mifepristone (all doses) vs Yuzpe Specific side effects ‐ abdominal pain · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	RR 0.76 [0.61, 0.95]	1 study · 1000 participants	Moderate
Mifepristone (all doses) vs Yuzpe Specific side effects ‐ spotting/bleeding after treatment · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	no estimate extracted	NR	No studies
Mifepristone (all doses) vs Yuzpe Menses ‐ delay · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	RR 2.83 [2.3, 3.47]	3 studies · 1924 participants	Moderate
Ulipristal acetate (all doses) vs levonorgestrel Observed number of pregnancies (all women) · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	RR 0.59 [0.35, 0.99]	2 studies · 3448 participants	High
Levonorgestrel vs Yuzpe Specific side effects ‐ Nausea · Women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	RR 0.4 [0.36, 0.44]	6 studies · 4750 participants	Moderate
Ulipristal acetate (all doses) vs levonorgestrel Any side effect · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	no estimate extracted	NR	No studies
Ulipristal acetate (all doses) vs levonorgestrel Specific side effects ‐ nausea · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	RR 1.14 [0.93, 1.41]	2 studies · 3770 participants	Moderate
Ulipristal acetate (all doses) vs levonorgestrel Specific side effects ‐ vomiting · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	RR 1 [0.14, 7.07]	1 study · 1549 participants	Moderate
Ulipristal acetate (all doses) vs levonorgestrel Specific side effects ‐ spotting/bleeding after treatment · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	RR 0.71 [0.23, 2.24]	1 study · 1549 participants	Moderate
Ulipristal acetate (all doses) vs levonorgestrel Menses ‐ early · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	RR 0.43 [0.37, 0.5]	2 studies · 3593 participants	Moderate
Ulipristal acetate (all doses) vs levonorgestrel Menses ‐ delay · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	RR 1.65 [1.42, 1.92]	2 studies · 3593 participants	High
Single‐dose levonorgestrel vs split‐dose levonorgestrel Observed number of pregnancies (all women) · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	RR 0.84 [0.53, 1.33]	3 studies · 6653 participants	Moderate
Single‐dose levonorgestrel vs split‐dose levonorgestrel Any side effect · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	no estimate extracted	NR	No studies
Single‐dose levonorgestrel vs split‐dose levonorgestrel Specific side effects ‐ nausea · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	RR 0.97 [0.88, 1.07]	3 studies · 6804 participants	Moderate
Single‐dose levonorgestrel vs split‐dose levonorgestrel Specific side effects ‐ vomiting · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	RR 1.01 [0.83, 1.22]	3 studies · 6804 participants	Moderate
Levonorgestrel vs Yuzpe Specific side effects ‐ Vomiting · Women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	RR 0.29 [0.24, 0.35]	5 studies · 3640 participants	Moderate
Single‐dose levonorgestrel vs split‐dose levonorgestrel Specific side effects ‐ spotting/bleeding after treatment · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	RR 1 [0.9, 1.12]	1 study · 2720 participants	Moderate
Single‐dose levonorgestrel vs split‐dose levonorgestrel Menses ‐ early · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	RR 0.67 [0.54, 0.82]	1 study · 1118 participants	High
Single‐dose levonorgestrel vs split‐dose levonorgestrel Menses ‐ delay · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	RR 1.18 [0.96, 1.46]	2 studies · 3784 participants	Low
Mid‐dose mifepristone (25 mg‐50 mg) vs low‐dose mifepristone (< 25 mg) Observed number of pregnancies (all women) · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	RR 0.73 [0.55, 0.97]	25 studies · 11914 participants	High
Mid‐dose mifepristone (25 mg‐50 mg) vs low‐dose mifepristone (< 25 mg) Any side effect · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	RR 1.31 [1.01, 1.7]	11 studies · 2464 participants	Moderate
Mid‐dose mifepristone (25 mg‐50 mg) vs low‐dose mifepristone (< 25 mg) Specific side effects ‐ nausea · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	RR 1.1 [0.97, 1.24]	13 studies · 7948 participants	Moderate
Mid‐dose mifepristone (25 mg‐50 mg) vs low‐dose mifepristone (< 25 mg) Specific side effects ‐ vomiting · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	RR 1.22 [0.68, 2.17]	6 studies · 6082 participants	Moderate
Mid‐dose mifepristone (25 mg‐50 mg) vs low‐dose mifepristone (< 25 mg) Specific side effects ‐ spotting/bleeding after treatment · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	RR 1.85 [1.55, 2.2]	11 studies · 5078 participants	High
Mid‐dose mifepristone (25 mg‐50 mg) vs low‐dose mifepristone (< 25 mg) Menses ‐ early · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	RR 1.09 [0.87, 1.36]	7 studies · 2136 participants	Low
Mid‐dose mifepristone (25 mg‐50 mg) vs low‐dose mifepristone (< 25 mg) Menses ‐ delay · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	RR 1.28 [1.11, 1.47]	21 studies · 11282 participants	Moderate
Levonorgestrel vs Yuzpe Specific side effects ‐ Spotting/bleeding after treatment · Women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	RR 1.82 [1.37, 2.41]	2 studies · 1614 participants	Moderate
Copper intrauterine device vs mifepristone (all doses) Observed number of pregnancies (all women) · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	RR 0.33 [0.04, 2.74]	2 studies · 395 participants	Low
Copper intrauterine device vs mifepristone (all doses) Any side effect · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	RR 0.06 [0, 0.99]	1 study · 285 participants	Low
Copper intrauterine device vs mifepristone (all doses) Specific side effects ‐ nausea · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	no estimate extracted	NR	No studies
Copper intrauterine device vs mifepristone (all doses) Specific side effects ‐ vomiting · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	no estimate extracted	NR	No studies
Copper intrauterine device vs mifepristone (all doses) Specific side effects ‐ lower abdominal pain · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	RR 73.61 [4.48, 1208.5]	1 study · 285 participants	Low
Copper intrauterine device vs mifepristone (all doses) Specific side effects ‐ spotting/bleeding after treatment · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	no estimate extracted	NR	No studies
Copper intrauterine device vs mifepristone (all doses) Menses ‐ delay · women seeking emergency contraception Interventions for emergency contraception (2019) · Cochrane	RR 0.23 [0.09, 0.64]	1 study · 284 participants	Low