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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
1,463 questions in 125 reviews · Anaesthesia
current versionsNo studies 197 · 13.5%Ungraded 203 · 13.9%Very low 307 · 21%Low 441 · 30.1%Moderate 245 · 16.7%High 70 · 4.8%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Intervention NR Amisulpride (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Droperidol (7 RCTs; 659 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 7 studies · 659 participants | Very low |
Intervention NR Haloperidol (2 RCTs; 99 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 2 studies · 99 participants | Very low |
Intervention NR Metoclopramide (3 RCTs; 150 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 3 studies · 150 participants | Very low |
Intervention NR Perphenazine (0 RCTs 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR NK1 receptor antagonists · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 1 participants | Ungraded |
Intervention NR Aprepitant (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Casopitant (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Fosaprepitant (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Promethazine (3 RCTs; 210 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 3 studies · 210 participants | Moderate |
Intervention NR Rolapitant (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Corticosteroids · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Dexamethasone (3 RCTs; 189 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 3 studies · 189 participants | Low |
Intervention NR Methylprednisolone (1 RCT; 96 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 1 study · 96 participants | Very low |
Intervention NR Antihistamines · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Dimenhydrinate (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Meclizine (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Promethazine (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Anticholinergics · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Scopolamine (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Anticholinergics · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Comparator · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Placebo · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Total studies: 21 RCTs Total participants: 3634 Number of treatments: 12 Geometry of the network** · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 21 studies · 3634 participants | Ungraded |
Intervention NR Dolasetron (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Granisetron (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Ondansetron (3 RCTs; 506 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 3 studies · 506 participants | Low |
Intervention NR Palonosetron (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Ramosetron (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Tropisetron (1 RCT; 97 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 1 study · 97 participants | Very low |
Intervention NR D2 receptor antagonists · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 2 participants | Ungraded |
Intervention NR Scopolamine (6 RCTs; 549 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 6 studies · 549 participants | Low |
Intervention NR Amisulpride (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Droperidol (5 RCTs; 682 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 5 studies · 682 participants | Very low |
Intervention NR Haloperidol (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Metoclopramide (1 RCT; 100 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 1 study · 100 participants | Low |
Intervention NR Perphenazine (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR NK1 receptor antagonists · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 1 participants | Ungraded |
Intervention NR Aprepitant (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Casopitant (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Fosaprepitant (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Rolapitant (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Comparator · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Corticosteroids · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Dexamethasone (1 RCT; 40 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 1 study · 40 participants | Low |
Intervention NR Methylprednisolone (1 RCT; 96 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 1 study · 96 participants | Very low |
Intervention NR Antihistamines · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Dimenhydrinate (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Meclizine (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Intervention NR Promethazine (0 RCTs; 0 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and… Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network… (2020) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |