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What do systematic reviews say?

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Evidence found and GRADE certainty

2,543 questions · 2,589 findings · 168 reviews · Schizophrenia

No studies found 601 · 23.2%GRADE not reported 446 · 17.2%Very low 721 · 27.8%Low 505 · 19.5%Moderate 274 · 10.6%High 42 · 1.6%

Summary of findings table ‐ Antipsychotic dose reduction vs dose continuation

Participants with at least some Side Effects · patients with schizophrenia

Summary of findings table ‐ Antipsychotic dose reduction showed no clear difference in adverse effects ‐ number of participants with at least 1 adverse… compared with dose continuation (moderate certainty).

1 finding from 1 review

VIDEO GAMES (COMMERCIAL NON‐EXERGAMES) (plus standard care) vs COGNITIVE REMEDIATION (plus standard care)

Cognitive function · patients with schizophrenia

VIDEO GAMES (COMMERCIAL NON‐EXERGAMES) (plus standard care) may leads to lower functioning: specific ‐ cognitive ‐ improved (MCCB, at least 1… compared with COGNITIVE REMEDIATION (plus standard care) (low certainty).

1 finding from 1 review

VIDEO GAMES (COMMERCIAL NON‐EXERGAMES) (plus standard care) vs COGNITIVE REMEDIATION (plus standard care)

Adverse effects*: leaving the study early ‐ did not leave · patients with schizophrenia

VIDEO GAMES (COMMERCIAL NON‐EXERGAMES) (plus standard care) showed no clear difference in adverse effects*: leaving the study early ‐ did not leave ‐ by end… compared with COGNITIVE REMEDIATION (plus standard care) (low certainty).

1 finding from 1 review