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Evidence found and GRADE certainty

250 questions · 288 findings · 13 reviews · Dental public health and special care

No studies found 73 · 25.3%GRADE not reported 90 · 31.3%Very low 90 · 31.3%Low 29 · 10.1%Moderate 6 · 2.1%High 0 · 0%

High-volume evacuation (HVE) vs No HVE

Reduction in level of contamination in aerosols (CFU) during ultrasonic scaling and air polishing at more than 1 foot from oral cavity (RCT) · People undergoing aerosol-generating procedures (AGPs) in a dental setting

It is very uncertain whether high-volume evacuation (HVE) changes reduction in level of contamination in aerosols (CFU) during… compared with no HVE (very low certainty).

1 finding from 1 review

Antimicrobial mouthwash and/or nasal spray (alone or in combination), any concentration, frequency or dosage vs No treatment or saline or water

Anosmia (or disturbance in sense of smell) · Patients with suspected or confirmed COVID-19 infection

The review found no eligible studies for this question.

1 finding from 1 review

Chlorhexidine (mouthrinse or gel), as part of oral hygiene care vs placebo or usual care

Duration of mechanical ventilation · Critically ill patients (adults and children) receiving mechanical ventilation in ICU

It is very uncertain whether chlorhexidine (mouthrinse or gel), as part of oral hygiene care changes duration of mechanical ventilation compared with placebo or usual care (very low certainty).

1 finding from 1 review

Antimicrobial coolant A (chlorhexidine) vs Distilled water coolant

Reduction in level of contamination in aerosols (CFU): chlorhexidine coolant vs distilled water during ultrasonic scaling · People undergoing aerosol-generating procedures (AGPs) in a dental setting

It is very uncertain whether chlorhexidine coolant changes reduction in level of contamination in aerosols (CFU): chlorhexidine… compared with distilled water coolant (very low certainty).

1 finding from 1 review

Chlorhexidine (mouthrinse or gel), as part of oral hygiene care vs placebo or usual care

Duration of ICU stay · Critically ill patients (adults and children) receiving mechanical ventilation in ICU

Chlorhexidine (mouthrinse or gel), as part of oral hygiene care showed no clear difference in duration of ICU stay compared with placebo or usual care (low certainty).

1 finding from 1 review

Laminar air flow with HEPA filter vs Without laminar flow or filter

Reduction in level of contamination in aerosols (CFU per cubic feet/min/patient) using Reyniers slit sampler 30 inches (76 cm) from floor · People undergoing aerosol-generating procedures (AGPs) in a dental setting

It is very uncertain whether laminar air flow with HEPA filter changes reduction in level of contamination in aerosols (CFU per cubic… compared with without laminar flow or filter (very low certainty).

1 finding from 1 review

Rubber dam vs No rubber dam

Reduction in level of contamination in aerosols (CFU) during restorative procedures at operator's left ear (RCT) · People undergoing aerosol-generating procedures (AGPs) in a dental setting

Rubber dam showed no clear difference in reduction in level of contamination in aerosols (CFU) during… compared with no rubber dam; GRADE not reported.

1 finding from 1 review

Powered toothbrushing (as part of comprehensive oral care) vs Manual toothbrushing

Duration of ICU stay · Critically ill patients receiving mechanical ventilation in ICU

Powered toothbrushing (as part of comprehensive oral care) showed no clear difference in duration of ICU stay compared with manual toothbrushing (standard oral care); GRADE not reported.

1 finding from 1 review

Any method, procedure or policy to reduce contaminated aerosols in dental clinics vs Any other method, no treatment or combination of methods

Reduction in volume of contaminated aerosols in the operative environment · Dental healthcare providers (dentist, dental surgery assistant, dental hygienist, dental technologist, dental laboratory staff, dental…

The review found no eligible studies for this question.

1 finding from 1 review

Antimicrobial mouthwash and/or nasal spray (alone or in combination), any concentration, frequency or dosage vs No treatment or saline or water

Change in viral load · Patients with suspected or confirmed COVID-19 infection

The review found no eligible studies for this question.

1 finding from 1 review

Antimicrobial mouthwash and/or nasal spray (alone or in combination), any concentration, frequency or dosage vs No treatment or saline or water

RECOVERY trial outcomes (mortality; hospitalisation status; use of ventilation; use of renal dialysis or haemofiltration) · Patients with suspected or confirmed COVID-19 infection

The review found no eligible studies for this question.

1 finding from 1 review

Powered toothbrushing (as part of comprehensive oral care) vs Manual toothbrushing

All‐cause mortality · Critically ill patients receiving mechanical ventilation in ICU

Powered toothbrushing (as part of comprehensive oral care) showed no clear difference in mortality compared with manual toothbrushing (standard oral care); GRADE not reported.

1 finding from 1 review

Toothbrushing (with or without antiseptics), as part of oral hygiene care vs No toothbrushing (with or without antiseptics)

Duration of mechanical ventilation · Critically ill adults receiving mechanical ventilation in ICU

Toothbrushing (with or without antiseptics), as part of oral hygiene… showed no clear difference in duration of mechanical ventilation compared with no toothbrushing (with or without antiseptics) (low certainty).

1 finding from 1 review