Steroids vs vitamin D
Steroid leads to higher number of participants achieving 'response' by IGA compared with vitamin D (high certainty).
- RR 2.09 [1.8, 2.41]3 studies · 1827 participantsHigh
Steroid leads to higher number of participants achieving 'response' by IGA compared with vitamin D (high certainty).
Steroid probably leads to lower number of participants withdrawing due to adverse events (AE) compared with vitamin D (moderate certainty).
Steroid probably leads to higher number of participants achieving 'response' by PGA compared with vitamin D (moderate certainty).
Steroid plus vitamin D probably leads to higher number of participants achieving 'clearance' by IGA compared with steroid (moderate certainty).
Steroid plus vitamin D probably leads to higher number of participants achieving 'response' by IGA compared with steroid (moderate certainty).
Steroid plus vitamin D showed no clear difference in number of participants withdrawing due to adverse events (AE) compared with steroid (moderate certainty).
Naftifine 1% cream once or twice daily showed no clear difference in relapse or recurrence Evidence of clinical or mycological infection… compared with placebo cream once or twice daily (low certainty).
It is very uncertain whether azoles changes adverse effects Reported by investigators 'and' or 'or' participants compared with allylamines (very low certainty).
It is very uncertain whether azoles changes relapse or recurrence Evidence of clinical and mycological relapse… compared with allylamines (very low certainty).
Azoles showed no clear difference in mycological cure Negative KOH microscopy and culture. Treatment… compared with moderate‐potent corticosteroid/azole combinations (low certainty).
Terbinafine 1% cream/gel may leads to higher clinical cure Resolution of clinical signs and symptoms. Treatment… compared with placebo cream/gel (low certainty).