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Evidence found and GRADE certainty

163 questions · 236 findings · 12 reviews · Periodontology

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No studies found 40 · 16.9%GRADE not reported 105 · 44.5%Very low 58 · 24.6%Low 28 · 11.9%Moderate 5 · 2.1%High 0 · 0%

Intensive periodontal treatment (subgingival SRP with or without other periodontal treatment) vs Supra-gingival scaling

Heart rate · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension

The review found no eligible studies for this question.

1 finding from 1 review
  • Effect of periodontal treatments on blood pressure 2021 · Cochrane All outcomes
    Heart rate was reported only by Higashi 2009 (periodontal treatment vs no treatment); no study in the intensive-treatment vs supra-gingival-scaling comparison reported heart rate.
    Studies not reported
    No studies found

Intensive periodontal treatment (subgingival SRP with or without other periodontal treatment) vs No treatment (no periodontal treatment)

Probing pocket depth · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension

Periodontal treatment (subgingival SRP with or without other… led to lower pocket probing depth (PPD) compared with no treatment (no periodontal treatment); GRADE not reported.

1 finding from 1 review

Intensive periodontal treatment (subgingival SRP with or without other periodontal treatment) vs Supra-gingival scaling

Plasma level of IL-6 (pg/mL) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension

Intensive periodontal treatment (subgingival SRP with or without… showed no clear difference in plasma level of IL-6 (pg/mL) compared with supra-gingival scaling; GRADE not reported.

3 findings from 1 review

Intensive periodontal treatment (subgingival SRP with or without other periodontal treatment) vs No treatment (no periodontal treatment)

Plasma level of hs-CRP (mg/L) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension

Periodontal treatment (subgingival SRP with or without other… showed no clear difference in plasma level of hs-CRP (mg/L) compared with no treatment (no periodontal treatment); GRADE not reported.

4 findings from 1 review
Show 1 more finding

Intensive periodontal treatment (subgingival SRP with or without other periodontal treatment) vs Supra-gingival scaling

Plasma level of hs-CRP (mg/L) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension

Intensive periodontal treatment (subgingival SRP with or without… showed no clear difference in plasma level of hs-CRP (mg/L) compared with supra-gingival scaling; GRADE not reported.

2 findings from 1 review

Intensive periodontal treatment (subgingival SRP with or without other periodontal treatment) vs Supra-gingival scaling

Probing pocket depth · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension

Intensive periodontal treatment (subgingival SRP with or without… led to lower pocket probing depth (PPD) compared with supra-gingival scaling; GRADE not reported.

3 findings from 1 review

Intensive periodontal treatment (subgingival SRP with or without other periodontal treatment) vs No treatment (no periodontal treatment)

Proportion of participants diagnosed with hypertension at trial completion · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension

The review found no eligible studies for this question.

1 finding from 1 review

Intensive periodontal treatment (subgingival SRP with or without other periodontal treatment) vs Supra-gingival scaling

Endothelial function (endothelial microparticles) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension

Intensive periodontal treatment (subgingival SRP with or without… led to lower endothelial function (endothelial microparticles) compared with supra-gingival scaling; GRADE not reported.

2 findings from 1 review

Intensive periodontal treatment (subgingival SRP with or without other periodontal treatment) vs Supra-gingival scaling

Clinical attachment level (CAL) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension

Intensive periodontal treatment (subgingival SRP with or without… led to lower clinical attachment level (CAL) compared with supra-gingival scaling; GRADE not reported.

3 findings from 1 review

Intensive periodontal treatment (subgingival SRP with or without other periodontal treatment) vs No treatment (no periodontal treatment)

Adverse events (participants with adverse events or withdrawals due to adverse events) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension
1 finding from 1 review
  • Effect of periodontal treatments on blood pressure 2021 · Cochrane All outcomes
    SoF 1 (Adverse effects): Only 1 study reported that 1 participant in the treatment group experienced a myocardial infarction during the study period. 1 study reported no adverse effects. The remaining 2 studies did not…
    2 studies · 294 participants
    Low

Intensive periodontal treatment (subgingival SRP with or without other periodontal treatment) vs Supra-gingival scaling

Percentage of bleeding on probing (BOP) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension

Intensive periodontal treatment (subgingival SRP with or without… led to lower bleeding on probing (BOP) compared with supra-gingival scaling; GRADE not reported.

2 findings from 1 review

Intensive periodontal treatment (subgingival SRP with or without other periodontal treatment) vs No treatment (no periodontal treatment)

Endothelial function · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension

Periodontal treatment (subgingival SRP with or without other… showed no clear difference in endothelial function (forearm blood flow) compared with no treatment (no periodontal treatment); GRADE not reported.

1 finding from 1 review

Intensive periodontal treatment (subgingival SRP with or without other periodontal treatment) vs No treatment (no periodontal treatment)

Plasma level of IL-6 (pg/mL) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension

Periodontal treatment (subgingival SRP with or without other… showed no clear difference in plasma level of IL-6 (pg/mL) compared with no treatment (no periodontal treatment); GRADE not reported.

3 findings from 1 review

Intensive periodontal treatment (subgingival SRP with or without other periodontal treatment) vs No treatment (no periodontal treatment)

Percentage of bleeding on probing (BOP) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension

Periodontal treatment (subgingival SRP with or without other… led to lower bleeding on probing (BOP) compared with no treatment (no periodontal treatment); GRADE not reported.

1 finding from 1 review
  • Effect of periodontal treatments on blood pressure 2021 · Cochrane All outcomes
    Long term · People diagnosed with periodontitis and other cardiovascular diseases except hypertension
    MD -36.80 [-46.47, -27.13]
    1 study · 48 participants
    GRADE not reported

Intensive periodontal treatment (subgingival SRP with or without other periodontal treatment) vs No treatment (no periodontal treatment)

Heart rate · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension

Periodontal treatment (subgingival SRP with or without other… showed no clear difference in heart rate compared with no treatment (no periodontal treatment); GRADE not reported.

1 finding from 1 review

Rubber/elastomeric cleaning stick plus toothbrushing vs Toothbrushing alone

Gingivitis · Adults, 16 years and older (dentate)

It is very uncertain whether rubber/elastomeric cleaning stick plus toothbrushing changes gingivitis (proportion of bleeding sites) compared with toothbrushing alone (very low certainty).

2 findings from 1 review

Rubber/elastomeric cleaning stick plus toothbrushing vs Flossing plus toothbrushing

Plaque · Adults, 16 years and older (dentate)

It is very uncertain whether rubber/elastomeric cleaning stick plus toothbrushing changes plaque compared with flossing plus toothbrushing (very low certainty).

1 finding from 1 review

Rubber/elastomeric cleaning stick plus toothbrushing vs Flossing plus toothbrushing

Gingivitis · Adults, 16 years and older (dentate)

It is very uncertain whether rubber/elastomeric cleaning stick plus toothbrushing changes gingivitis (gingival index) compared with flossing plus toothbrushing (very low certainty).

2 findings from 1 review