Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

309 questions · 325 findings · 45 reviews · Acute Respiratory Infections

No studies found 38 · 11.7%GRADE not reported 31 · 9.5%Very low 54 · 16.6%Low 78 · 24%Moderate 106 · 32.6%High 18 · 5.5%

Intervention not reported

Fever after initiation of treatment ( · children with no influenza A infection (prevention) or with influenza A infection (treatment)

The intervention probably leads to lower fever after initiation of treatment ( (moderate certainty).

1 finding from 1 review

Intervention not reported

Cough after initiation of treatment ( · children with no influenza A infection (prevention) or with influenza A infection (treatment)

The intervention showed no clear difference in cough after initiation of treatment ( (moderate certainty).

1 finding from 1 review

Zinc vs placebo

Risk of adverse events, including those that may be due to zinc supplements Duration of · adults and children with colds and/or upper respiratory infections
1 finding from 1 review

Zinc vs placebo

Risk of serious adverse events, including those that may be complications of the common cold · adults and children with colds and/or upper respiratory infections

The review found no eligible studies for this question.

1 finding from 1 review

Vitamin A vs placebo

Incidence of acute URTIs during the study period (the number of acute URTIs over a period of time) · children up to the age of 7 at risk of upper respiratory tract infection

Summary of findings table ‐ Vitamin A supplements showed no clear difference in incidence of acute URTIs during the study period (the number of… compared with placebo (low certainty).

1 finding from 1 review