Findings

What do systematic reviews say?

114 questions · 114 findings · 9 reviews · Eyes and Vision

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No studies found 51 · 44.7%GRADE not reported 5 · 4.4%Very low 18 · 15.8%Low 21 · 18.4%Moderate 18 · 15.8%High 1 · 0.9%

Low‐ vs high‐energy diode trans‐scleral cyclophotocoagulation

Mean change in intraocular pressure · people with primary open‐angle glaucoma and no previous glaucoma surgery

1 finding from 1 review

Cyclodestructive procedures for non‐refractory glaucoma 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 79 participants
Low

Low‐ vs high‐energy diode trans‐scleral cyclophotocoagulation

Decrease in visual acuity · people with primary open‐angle glaucoma and no previous glaucoma surgery

Low‐ showed no clear difference in decrease in visual acuity compared with high‐energy diode trans‐scleral cyclophotocoagulation (low certainty).

1 finding from 1 review

Cyclodestructive procedures for non‐refractory glaucoma 2018 · Cochrane Headline outcomes only
RR 1.22 [0.54, 2.76]
1 study · 79 participants
Low

Low‐ vs high‐energy diode trans‐scleral cyclophotocoagulation

Mean visual field · people with primary open‐angle glaucoma and no previous glaucoma surgery

The review found no eligible studies for this question.

1 finding from 1 review

Cyclodestructive procedures for non‐refractory glaucoma 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Low‐ vs high‐energy diode trans‐scleral cyclophotocoagulation

Mean number of antiglaucoma medications at 1‐year · people with primary open‐angle glaucoma and no previous glaucoma surgery

1 finding from 1 review

Cyclodestructive procedures for non‐refractory glaucoma 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 79 participants
Moderate

Low‐ vs high‐energy diode trans‐scleral cyclophotocoagulation

Proportion needing additional glaucoma surgery at 1‐year · people with primary open‐angle glaucoma and no previous glaucoma surgery

Low‐ showed no clear difference in additional glaucoma surgery compared with high‐energy diode trans‐scleral cyclophotocoagulation (low certainty).

1 finding from 1 review

Cyclodestructive procedures for non‐refractory glaucoma 2018 · Cochrane Headline outcomes only
RR 0.76 [0.31, 1.84]
1 study · 79 participants
Low

Low‐ vs high‐energy diode trans‐scleral cyclophotocoagulation

Adverse events: atonic pupil · people with primary open‐angle glaucoma and no previous glaucoma surgery

Low‐ showed no clear difference in adverse events: atonic pupil compared with high‐energy diode trans‐scleral cyclophotocoagulation (low certainty).

1 finding from 1 review

Cyclodestructive procedures for non‐refractory glaucoma 2018 · Cochrane Headline outcomes only
RR 0.89 [0.47, 1.68]
1 study · 92 participants
Low

Neuroprotection vs control

Outcomes* · people with open‐angle glaucoma

The review found no eligible studies for this question.

1 finding from 1 review

Neuroprotection for treatment of glaucoma in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Neuroprotection vs control

Progression of visual field loss (worsening of one or more stages, accordingto the Glaucoma Staging System‐2) (at 12 months) · people with open‐angle glaucoma

It is very uncertain whether neuroprotection changes visual field: the proportion of participants with progression of… compared with control (very low certainty).

1 finding from 1 review

Neuroprotection for treatment of glaucoma in adults 2017 · Cochrane Headline outcomes only
RR 0.35 [0.14, 0.86]
1 study · 101 participants
Very low

Neuroprotection vs control

Decrease in visual acuity · people with open‐angle glaucoma

The review found no eligible studies for this question.

1 finding from 1 review

Neuroprotection for treatment of glaucoma in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Neuroprotection vs control

Mean intraocular pressure · people with open‐angle glaucoma

It is very uncertain whether neuroprotection changes intraocular pressure: mean IOP at 4 years' compared with control (very low certainty).

1 finding from 1 review

Neuroprotection for treatment of glaucoma in adults 2017 · Cochrane Headline outcomes only
MD 0.2
1 study · 91 participants
Very low

Neuroprotection vs control

Vertical cup‐disc ratio: the proportion of participants with asymmetrical vertical cup‐disc ratio greater than 0.3 at 4 years' · people with open‐angle glaucoma

The review found no eligible studies for this question.

1 finding from 1 review

Neuroprotection for treatment of glaucoma in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Neuroprotection vs control

Adverse effects: ocular allergy to the study medication requiring discontinuation up to 4 years' · people with open‐angle glaucoma

It is very uncertain whether neuroprotection changes adverse effects: ocular allergy to the study medication requiring… compared with control (very low certainty).

1 finding from 1 review

Neuroprotection for treatment of glaucoma in adults 2017 · Cochrane Headline outcomes only
RR 5.32 [1.64, 17.26]
1 study · 178 participants
Very low

Neuroprotection vs control

Quality of life measures · people with open‐angle glaucoma

The review found no eligible studies for this question.

1 finding from 1 review

Neuroprotection for treatment of glaucoma in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Neuroprotection vs control

Cost / economic data · people with open‐angle glaucoma

The review found no eligible studies for this question.

1 finding from 1 review

Neuroprotection for treatment of glaucoma in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found