Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,545 questions · 2,661 findings · 317 reviews

No studies found 608 · 22.8%GRADE not reported 505 · 19%Very low 695 · 26.1%Low 540 · 20.3%Moderate 249 · 9.4%High 64 · 2.4%

Any intervention for KCOT (e.g. enucleation), alone or combined with an adjunctive therapy (ostectomy, cryotherapy, or Carnoy's solution) vs A different intervention (e.g. enucleation versus marsupialisation), or the same surgical intervention without the adjunctive therapy

Outcome not reported · Adults over the age of 18 with a validated diagnosis of solitary keratocystic odontogenic tumours (KCOT) arising in the jaw bones of the…

The review found no eligible studies for this question.

1 finding from 1 review

Surgery vs preoperative pharmacological therapy and surgery

Disease‐related complications Intubation difficulties requiring postponement of surgery · adults with growth‐hormone secreting pituitary adenomas

It is very uncertain whether surgery alone changes disease‐related complications Intubation difficulties requiring… compared with preoperative pharmacological therapy and surgery (very low certainty).

1 finding from 1 review

ARP with xenograft (bone graft) vs Extraction alone

Marginal bone level change · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…
1 finding from 1 review

Educational intervention with information and practical components (theoretical oral health education plus practical skills training) for nursing staff and/or residents vs (Optimised) usual care

Adverse effects of the interventions · Nursing home residents (mean age 78.3 to 86.0 years; more than 66% women; 62.1% to 87.3% with dental prostheses)

The review found no eligible studies for this question.

1 finding from 1 review

Any experimental intervention (surgical or non-surgical) vs None (placebo or no treatment)

Healing of osteonecrosis - improvement ('healed' or 'improved' vs 'unchanged' or 'worse') · People of any age and either sex, in any setting, with BRONJ; bisphosphonate exposure past or current; includes people with cancer and…

The review found no eligible studies for this question.

1 finding from 1 review