Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

107 questions · 138 findings · 18 reviews · Dental caries

No studies found 23 · 16.7%GRADE not reported 94 · 68.1%Very low 14 · 10.1%Low 6 · 4.3%Moderate 1 · 0.7%High 0 · 0%

Pre-operative radiotherapy (plus surgery) vs surgery

Locoregional control · People with primary squamous cell carcinoma of the oral cavity (ICD-O C01-C06) or oropharynx (ICD-O C09-C10); head and neck cancer trials…

Pre-operative radiotherapy (plus surgery) showed no clear difference in locoregional control compared with surgery alone; GRADE not reported.

1 finding from 1 review

Altered fractionation radiotherapy vs Chemoradiotherapy (concurrent, standard fractionation)

Outcome not reported · People with primary squamous cell carcinoma of the oral cavity (ICD-O C01-C06) or oropharynx (ICD-O C09-C10); head and neck cancer trials…

The review found no eligible studies for this question.

1 finding from 1 review

Potassium containing toothpaste (5% potassium nitrate) vs Control toothpaste (without potassium)

Tactile sensitivity (method a, ordinal scale) · Healthy human adults (18 years or more) with dentine hypersensitivity from exposed root surfaces

Potassium containing toothpaste (5% potassium nitrate) led to lower tactile sensitivity (method a, ordinal scale) compared with control toothpaste (without potassium); GRADE not reported.

1 finding from 1 review

Potassium containing toothpaste (5% potassium nitrate) vs Control toothpaste (without potassium)

Thermal sensitivity · Healthy human adults (18 years or more) with dentine hypersensitivity from exposed root surfaces

Potassium containing toothpaste (5% potassium nitrate) led to lower thermal sensitivity compared with control toothpaste (without potassium); GRADE not reported.

1 finding from 1 review

Potassium containing toothpaste (5% potassium nitrate) vs Control toothpaste (without potassium)

Subjective assessment of sensitivity · Healthy human adults (18 years or more) with dentine hypersensitivity from exposed root surfaces

Potassium containing toothpaste (5% potassium nitrate) showed no clear difference in subjective assessment of sensitivity compared with control toothpaste (without potassium); GRADE not reported.

1 finding from 1 review

Potassium containing toothpaste (5% potassium nitrate) vs Control toothpaste (without potassium)

Air blast sensitivity · Healthy human adults (18 years or more) with dentine hypersensitivity from exposed root surfaces

Potassium containing toothpaste (5% potassium nitrate) led to lower air blast sensitivity compared with control toothpaste (without potassium); GRADE not reported.

1 finding from 1 review

Potassium containing toothpaste (5% potassium nitrate) vs Control toothpaste (without potassium)

Tactile sensitivity (method b, continuous probe) · Healthy human adults (18 years or more) with dentine hypersensitivity from exposed root surfaces

Potassium containing toothpaste (5% potassium nitrate) led to higher tactile sensitivity (method b, continuous probe) compared with control toothpaste (without potassium); GRADE not reported.

1 finding from 1 review