Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

929 questions · 946 findings · 295 reviews · Headline outcomes only

No studies found 150 · 15.9%GRADE not reported 47 · 5%Very low 312 · 33%Low 262 · 27.7%Moderate 138 · 14.6%High 37 · 3.9%

Steroid therapy in first episode of nephrotic syndrome: 3 months or more vs 2 months of therapy

Number of children relapsing by 12 to 24 months · children with nephrotic syndrome

Steroid therapy in first episode of nephrotic syndrome: 3 months or… may leads to lower number of children relapsing by 12 to 24 months compared with 2 months of therapy (low certainty).

1 finding from 1 review

Steroid therapy in first episode of nephrotic syndrome: 3 months or more vs 2 months of therapy

Number with frequent relapses by 12 to 24 months stratified by risk of selection bias: Low risk of selection bias · children with nephrotic syndrome

Steroid therapy in first episode of nephrotic syndrome: 3 months or… showed no clear difference in number with frequent relapses by 12 to 24 months stratified by risk… compared with 2 months of therapy (high certainty).

1 finding from 1 review

Steroid therapy in first episode of nephrotic syndrome: 3 months or more vs 2 months of therapy

Number with frequent relapses by 12 to 24 months stratified by risk of bias for allocation concealment: unclear or high risk of bias for allocation bias · children with nephrotic syndrome

Steroid therapy in first episode of nephrotic syndrome: 3 months or… may leads to lower number with frequent relapses by 12 to 24 months stratified by risk… compared with 2 months of therapy (low certainty).

1 finding from 1 review

Steroid therapy in first episode of nephrotic syndrome: 3 months or more vs 2 months of therapy

Adverse events: psychological disorders · children with nephrotic syndrome

Steroid therapy in first episode of nephrotic syndrome: 3 months or… showed no clear difference in adverse events: psychological disorders compared with 2 months of therapy (low certainty).

1 finding from 1 review

Steroid therapy in first episode of nephrotic syndrome: 3 months or more vs 2 months of therapy

Adverse events: hypertension · children with nephrotic syndrome

Steroid therapy in first episode of nephrotic syndrome: 3 months or… showed no clear difference in adverse events: hypertension compared with 2 months of therapy (moderate certainty).

1 finding from 1 review

Steroid therapy in first episode of nephrotic syndrome: 3 months or more vs 2 months of therapy

Adverse events: Cushing's syndrome · children with nephrotic syndrome

Steroid therapy in first episode of nephrotic syndrome: 3 months or… showed no clear difference in adverse events: Cushing's syndrome compared with 2 months of therapy (moderate certainty).

1 finding from 1 review

Infliximab combined with purine analogues vs purine analogues

Clinical relapse · Participants with Crohn's disease in remission

Infliximab combined with purine analogues probably leads to lower clinical relapse (at 48 weeks, CDAI of 150 or greater together with… compared with purine analogues (moderate certainty).

1 finding from 1 review

Summary of findings for the main comparison: comprehensive care programmes vs usual care

Parent health, functioning, and quality of life Patient‐Reported Outcomes Measurement Information System (PROMIS) (higher scores = more of the outcome of interest, which can mean improvement or deterioration depending on the outcome) · children with medical complexity
1 finding from 1 review

Pressure‐garment therapy (PGT) vs no treatment/lanolin

Scar improvement (POSAS) (0–10, higher score = more severe scarring) · people with burn wounds likely to develop hypertrophic scarring
2 findings from 1 review

Pressure‐garment therapy (PGT) plus silicone vs no treatment/lanolin

Scar improvement (POSAS) (0–10, higher score = more severe scarring) · people with burn wounds likely to develop hypertrophic scarring
2 findings from 1 review

Pressure‐garment therapy (PGT) plus silicone vs silicone

Scar improvement (POSAS) (0–10, higher score = more severe scarring) · people with burn wounds likely to develop hypertrophic scarring
2 findings from 1 review