Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

115 questions · 123 findings · 9 reviews · Dementia and Cognitive Improvement

No studies found 13 · 10.6%GRADE not reported 11 · 8.9%Very low 13 · 10.6%Low 25 · 20.3%Moderate 37 · 30.1%High 24 · 19.5%

Rivastigmine vs placebo

Risk for at least one adverse event per patient · Apathy in people with mild‐to‐moderate Alzheimer's disease

Rivastigmine probably leads to higher incidence of adverse events (at least one adverse event by 26 weeks) compared with placebo (moderate certainty).

1 finding from 1 review

Rivastigmine vs placebo

Quality of life of patients or carers (measured using NPI‐D carer distress scale (change from baseline at 24 weeks) · Apathy in people with mild‐to‐moderate Alzheimer's disease
1 finding from 1 review