Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

118 questions · 119 findings · 8 reviews · HIV/AIDS

No studies found 0 · 0%GRADE not reported 5 · 4.2%Very low 20 · 16.8%Low 41 · 34.5%Moderate 49 · 41.2%High 4 · 3.4%

Lactobacillus vs placebo

Episodes of confirmed vaginal candidiasis fungal smear · prevention and treatment of vulvovaginal candidiasis in women with HIV infection

Lactobacillus showed no clear difference in episodes of confirmed vaginal candidiasis fungal smear compared with placebo (low certainty).

1 finding from 1 review

Clotrimazole (partially absorbed from GI tract) vs placebo

Episodes of confirmed vaginal candidiasis fungal smear · prevention and treatment of vulvovaginal candidiasis in women with HIV infection

Clotrimazole showed no clear difference in episode of confirmed vaginal candidiasis fungal smear compared with placebo (low certainty).

1 finding from 1 review

Azoles vs placebo

Episodes of confirmed vaginal candidiasis fungal smear · prevention and treatment of vulvovaginal candidiasis in women with HIV infection

It is very uncertain whether azoles changes episode of confirmed vaginal candidiasis Fungal Smears compared with placebo (very low certainty).

1 finding from 1 review

Intervention not reported

Episode of confirmed vaginal candidiasis ‐ Upto 12 months Fungal smears · prevention and treatment of vulvovaginal candidiasis in women with HIV infection

The intervention probably leads to lower episode of confirmed vaginal candidiasis ‐ Upto 12 months Fungal… (moderate certainty).

1 finding from 1 review

Intervention not reported

Episode of confirmed vaginal candidiasis ‐ Upto 24 Months Fungal smears · prevention and treatment of vulvovaginal candidiasis in women with HIV infection

The intervention probably leads to lower episode of confirmed vaginal candidiasis ‐ Upto 24 Months Fungal… (moderate certainty).

1 finding from 1 review

Intervention not reported

Emergence of non albicans species of Candida ‐ At 12 months Fungal Smears · prevention and treatment of vulvovaginal candidiasis in women with HIV infection

The intervention showed no clear difference in emergence of non albicans species of Candida ‐ At 12 months Fungal… (moderate certainty).

1 finding from 1 review

Intervention not reported

Emergence of non albicans species of Candida ‐ At 24 months Fungal Smears · prevention and treatment of vulvovaginal candidiasis in women with HIV infection

The intervention showed no clear difference in emergence of non albicans species of Candida ‐ At 24 months Fungal… (moderate certainty).

1 finding from 1 review

Intervention not reported

In Vitro resistance to azoles ‐ Candida albicans MIC >= 64 micrograms/ml · prevention and treatment of vulvovaginal candidiasis in women with HIV infection

The intervention showed no clear difference in in Vitro resistance to azoles ‐ Candida albicans MIC >= 64… (moderate certainty).

1 finding from 1 review

Intervention not reported

In Vitro resistance to azoles ‐ Non albicans Candida MIC>= 64 micrograms/ml · prevention and treatment of vulvovaginal candidiasis in women with HIV infection

The intervention probably leads to higher in Vitro resistance to azoles ‐ Non albicans Candida MIC>= 64… (moderate certainty).

1 finding from 1 review

Lactobacillus vs Clotrimazole 10 mg (partially absorbed)

Episodes of confirmed vaginal candidiasis fungal smear · prevention and treatment of vulvovaginal candidiasis in women with HIV infection

Lactobacillus showed no clear difference in episodes of confirmed vaginal candidiasis fungal smear compared with clotrimazole (low certainty).

1 finding from 1 review