Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

628 questions · 671 findings · 31 reviews · Effective Practice and Organisation of Care

No studies found 215 · 32%GRADE not reported 29 · 4.3%Very low 156 · 23.2%Low 165 · 24.6%Moderate 69 · 10.3%High 37 · 5.5%

Lay health worker‐led psychosocial interventions vs enhanced usual care

Functional impairment · women with perinatal depression

Lay health worker‐led psychosocial interventions showed no clear difference in functional impairment ‐ intermediate term (1 to 6 months post… compared with enhanced usual care (low certainty).

1 finding from 1 review

Lay health worker‐led psychosocial interventions vs enhanced usual care

Service utilisation ‐ maternal or child hospitalisations ‐ intermediate term (1 to 6 months post intervention) · women with perinatal depression

It is very uncertain whether lay health worker‐led psychosocial interventions changes service utilisation ‐ maternal or child hospitalisations ‐… compared with enhanced usual care (very low certainty).

1 finding from 1 review

Lay health worker‐led psychological interventions vs usual care

Recovery from CMD ‐ intermediate term (1 to 6 months post intervention) Recovery defined by GDS ≤ 11a; HDRS < 7b; HDRS < 8c; PHQ‐9 < 6d; PHQ‐9 < 5 or 50% reduction from baselinee (RR > 1 denotes greater likelihood of recovery) · adults with common mental disorders

Lay health worker‐led psychological interventions may leads to higher recovery from CMDs ‐ intermediate term (1 to 6 months post… compared with usual care (low certainty).

1 finding from 1 review

Lay health worker‐led psychological interventions vs usual care

Prevalence of CMDs ‐ intermediate term (1 to 6 months post intervention) Diagnosis defined by SRQ‐20 > 7b; PHQ‐9 ≥ 11d (RR < 1 denotes lower prevalence compared to control) · adults with common mental disorders

Lay health worker‐led psychological interventions may leads to lower prevalence of CMDs ‐ intermediate term (1 to 6 months post… compared with usual care (low certainty).

1 finding from 1 review

Lay health worker‐led psychological interventions vs usual care

Severity of CMD symptoms (including anxiety and depression) ‐ intermediate term (1 to 6 months post intervention) Measured by PHQ‐9a,d,f; SRQ‐20b (higher score, higher severity) · adults with common mental disorders
1 finding from 1 review

Lay health worker‐led psychological interventions vs usual care

Prevalence of PTSD · adults with post‐traumatic stress and CMDs

It is very uncertain whether lay health worker‐led psychological interventions changes prevalence of PTSD ‐ intermediate term (1 to 6 months) Diagnosis… compared with usual care (very low certainty).

1 finding from 1 review

Lay health worker‐led psychological interventions vs usual care

PTS symptoms ‐ intermediate term (1 to 6 months post intervention) PCL‐5a,d,e; PCL‐6f; Post‐traumatic Stress Diagnostic Scaleb (higher score = higher severity) · adults with post‐traumatic stress and CMDs
1 finding from 1 review

Lay health worker‐led psychological interventions vs usual care

Depression symptoms ‐ intermediate term (1 to 6 months post intervention) GHQ‐12a; PHQ‐9d,e,f; self‐reporting questionnaireh (higher score = higher severity) · adults with post‐traumatic stress and CMDs
1 finding from 1 review

Lay health worker‐led psychological interventions vs usual care

Quality of life ‐ intermediate term (1 to 6 months post intervention) EQ‐5Di; SF‐36c,m; WHOQOL‐BREFe,j,n (higher score = better quality of life) · adults with post‐traumatic stress and CMDs
1 finding from 1 review

Lay health worker‐led psychological interventions vs usual care

Hospital admissions · adults with post‐traumatic stress and CMDs

It is very uncertain whether lay health worker‐led psychological interventions changes service utilisation ‐ hospital admissions (1 to 6 months post… compared with usual care (very low certainty).

1 finding from 1 review

Lay health worker‐led psychological interventions vs usual care

Functional impairment ‐ not measured · adults with common mental disorders

Lay health worker‐led psychological interventions showed no clear difference in functional impairment/disability ‐ intermediate term (1 to 6 months… compared with usual care (low certainty).

1 finding from 1 review

Lay health worker‐led psychological interventions vs usual care

Service utilisation · adults with common mental disorders

It is very uncertain whether lay health worker‐led psychological interventions changes service utilisation (1 to 6 months post intervention) compared with usual care (very low certainty).

1 finding from 1 review

Lay health worker‐led psychological interventions vs usual care

Adverse events RR < 1 indicates lower risk of adverse events · adults with common mental disorders

Lay health worker‐led psychological interventions may leads to lower adverse events RR < 1 indicates lower risk of adverse events compared with usual care (low certainty).

1 finding from 1 review

Home‐based record combined with other interventions vs usual care

Proportion of children who received DTP3 or Penta 3 ‐ HBRf only · children aged 1 year

Home‐based record combined with other interventions may leads to higher proportion of children who received DTP3 or Penta 3 ‐ HBRf only compared with routine care (low certainty).

1 finding from 1 review