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Evidence found and GRADE certainty

502 questions · 519 findings · 57 reviews · Hepato-Biliary

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No studies found 131 · 25.2%GRADE not reported 11 · 2.1%Very low 302 · 58.2%Low 46 · 8.9%Moderate 27 · 5.2%High 2 · 0.4%

Distal splenorenal shunt vs endoscopic intervention

Mortality due to rebleeding · participants with cirrhosis and with previous oesophagogastric variceal bleeding

It is very uncertain whether distal splenorenal shunt changes mortality due to rebleeding compared with endoscopic intervention (very low certainty).

1 finding from 1 review

Distal splenorenal shunt vs endoscopic intervention

Acute hepatic encephalopathy · participants with cirrhosis and with previous oesophagogastric variceal bleeding

It is very uncertain whether distal splenorenal shunt changes acute hepatic encephalopathy compared with endoscopic intervention (very low certainty).

1 finding from 1 review

Distal splenorenal shunt vs endoscopic intervention

Chronic hepatic encephalopathy · participants with cirrhosis and with previous oesophagogastric variceal bleeding

It is very uncertain whether distal splenorenal shunt changes chronic hepatic encephalopathy compared with endoscopic intervention (very low certainty).

1 finding from 1 review

Transjugular intrahepatic portosystemic shunts vs endoscopic intervention with or without medical treatment

All‐cause mortality · participants with cirrhosis and with previous oesophagogastric variceal bleeding

It is very uncertain whether transjugular intrahepatic portosystemic shunt changes all‐cause mortality compared with endoscopic intervention with or without medical treatment (very low certainty).

1 finding from 1 review

Portosystemic shunts vs endoscopic intervention with or without medical treatment

Rebleeding · participants with cirrhosis and with previous oesophagogastric variceal bleeding

It is very uncertain whether portosystemic shunts changes rebleeding compared with endoscopic intervention with or without medical treatment (very low certainty).

1 finding from 1 review

Transjugular intrahepatic portosystemic shunts vs endoscopic intervention with or without medical treatment

Rebleeding · participants with cirrhosis and with previous oesophagogastric variceal bleeding

It is very uncertain whether transjugular intrahepatic portosystemic shunt changes rebleeding compared with endoscopic intervention with or without medical treatment (very low certainty).

1 finding from 1 review

Transjugular intrahepatic portosystemic shunts vs endoscopic intervention with or without medical treatment

Health‐related quality of life · participants with cirrhosis and with previous oesophagogastric variceal bleeding

The review found no eligible studies for this question.

1 finding from 1 review

Transjugular intrahepatic portosystemic shunts vs endoscopic intervention with or without medical treatment

Mortality due to rebleeding · participants with cirrhosis and with previous oesophagogastric variceal bleeding

It is very uncertain whether transjugular intrahepatic portosystemic shunt changes mortality due to rebleeding compared with endoscopic intervention with or without medical treatment (very low certainty).

1 finding from 1 review

Transjugular intrahepatic portosystemic shunts vs endoscopic intervention with or without medical treatment

Acute hepatic encephalopathy · participants with cirrhosis and with previous oesophagogastric variceal bleeding

It is very uncertain whether transjugular intrahepatic portosystemic shunt changes acute hepatic encephalopathy compared with endoscopic intervention with or without medical treatment (very low certainty).

1 finding from 1 review

Transjugular intrahepatic portosystemic shunts vs endoscopic intervention with or without medical treatment

Chronic hepatic encephalopathy · participants with cirrhosis and with previous oesophagogastric variceal bleeding

It is very uncertain whether transjugular intrahepatic portosystemic shunt changes chronic hepatic encephalopathy compared with endoscopic intervention with or without medical treatment (very low certainty).

1 finding from 1 review

Portosystemic shunts vs endoscopic intervention with or without medical treatment

Mortality due to rebleeding · participants with cirrhosis and with previous oesophagogastric variceal bleeding

It is very uncertain whether portosystemic shunts changes mortality due to rebleeding compared with endoscopic intervention with or without medical treatment (very low certainty).

1 finding from 1 review

Portosystemic shunts vs endoscopic intervention with or without medical treatment

Acute hepatic encephalopathy · participants with cirrhosis and with previous oesophagogastric variceal bleeding

It is very uncertain whether portosystemic shunts changes acute hepatic encephalopathy compared with endoscopic intervention with or without medical treatment (very low certainty).

1 finding from 1 review

Portosystemic shunts vs endoscopic intervention with or without medical treatment

Chronic hepatic encephalopathy · participants with cirrhosis and with previous oesophagogastric variceal bleeding

It is very uncertain whether portosystemic shunts changes chronic hepatic encephalopathy compared with endoscopic intervention with or without medical treatment (very low certainty).

1 finding from 1 review

Total shunt vs endoscopic intervention

All‐cause mortality · participants with cirrhosis and with previous oesophagogastric variceal bleeding

It is very uncertain whether total shunt changes all‐cause mortality compared with endoscopic intervention (very low certainty).

1 finding from 1 review

Transarterial embolisation and transarterial chemoembolisation vs no intervention

Death during study period · people with liver metastases

It is very uncertain whether transarterial embolisation and transarterial chemoembolisation changes mortality at 44 months from trial entry Number of participants compared with no intervention (very low certainty).

1 finding from 1 review