Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

347 questions · 354 findings · 22 reviews

No studies found 100 · 28.2%GRADE not reported 37 · 10.5%Very low 115 · 32.5%Low 64 · 18.1%Moderate 23 · 6.5%High 15 · 4.2%

HALOPERIDOL vs RISPERIDONE

Repeated need for rapid tranquillisation ‐ needing additional benzodiazepine · patients with psychosis‐induced aggression or agitation

HALOPERIDOL showed no clear difference in repeated need for rapid tranquillisation ‐ needing additional… compared with OTHER ANTIPSYCHOTIC: h. RISPERIDONE (low certainty).

1 finding from 1 review

HALOPERIDOL vs RISPERIDONE

Specific behaviours ‐ agitation >50% reduction in PANSS‐EC score · patients with psychosis‐induced aggression or agitation

HALOPERIDOL showed no clear difference in specific behaviours ‐ agitation >50% reduction in PANSS‐EC score compared with OTHER ANTIPSYCHOTIC: h. RISPERIDONE (low certainty).

1 finding from 1 review

HALOPERIDOL vs RISPERIDONE

Global outcome ‐ rated as severe ‐ CGI‐S · patients with psychosis‐induced aggression or agitation

It is very uncertain whether HALOPERIDOL changes global outcome ‐ rated as severe ‐ CGI‐S compared with OTHER ANTIPSYCHOTIC: h. RISPERIDONE (very low certainty).

1 finding from 1 review

HALOPERIDOL vs RISPERIDONE

Adverse effects: specific ‐ acute dystonia · patients with psychosis‐induced aggression or agitation

It is very uncertain whether HALOPERIDOL changes adverse effects: Specific ‐ acute dystonia during 24 hours compared with OTHER ANTIPSYCHOTIC: h. RISPERIDONE (very low certainty).

1 finding from 1 review

HALOPERIDOL vs OTHER ANTIPSYCHOTIC: h. THIOTHIXENE

Repeated need for rapid tranquillisation · patients with psychosis‐induced aggression or agitation

It is very uncertain whether HALOPERIDOL changes repeated need for rapid tranquillisation compared with OTHER ANTIPSYCHOTIC: i. THIOTHIXENE (very low certainty).

1 finding from 1 review

HALOPERIDOL vs OTHER ANTIPSYCHOTIC: h. THIOTHIXENE

Global outcome No improvement at 1 hour · patients with psychosis‐induced aggression or agitation

It is very uncertain whether HALOPERIDOL changes global outcome No improvement at 1 hour compared with OTHER ANTIPSYCHOTIC: i. THIOTHIXENE (very low certainty).

1 finding from 1 review