Findings

What do systematic reviews say?

106 questions · 106 findings · 19 reviews

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No studies found 16 · 15.1%GRADE not reported 9 · 8.5%Very low 22 · 20.8%Low 25 · 23.6%Moderate 25 · 23.6%High 9 · 8.5%

Remifentanil (PCA) vs epidural/CSE

Satisfaction with pain relief · women in labour with planned vaginal delivery

1 finding from 1 review

Patient‐controlled analgesia with remifentanil versus alternative parenteral methods for pain management in labour 2017 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 2135 participants
Very low

Remifentanil (PCA) vs epidural/CSE

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · women in labour with planned vaginal delivery

1 finding from 1 review

Patient‐controlled analgesia with remifentanil versus alternative parenteral methods for pain management in labour 2017 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 235 participants
Low

Remifentanil (PCA) vs epidural/CSE

Caesarean section · women in labour with planned vaginal delivery

Remifentanil (PCA) showed no clear difference in rate of caesarean delivery compared with epidural/CSE (moderate certainty).

1 finding from 1 review

Patient‐controlled analgesia with remifentanil versus alternative parenteral methods for pain management in labour 2017 · Cochrane Headline outcomes only
RR 1 [0.82, 1.22]
9 studies · 1578 participants
Moderate

Remifentanil (PCA) vs epidural/CSE

Maternal apnoea · women in labour with planned vaginal delivery

1 finding from 1 review

Patient‐controlled analgesia with remifentanil versus alternative parenteral methods for pain management in labour 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 38 participants
Very low

Remifentanil (PCA) vs epidural/CSE

Maternal respiratory depression (< 9, < 8 breaths/min) · women in labour with planned vaginal delivery

Remifentanil (PCA) showed no clear difference in maternal respiratory depression (< 9, < 8 breaths/min) compared with epidural/CSE (low certainty).

1 finding from 1 review

Patient‐controlled analgesia with remifentanil versus alternative parenteral methods for pain management in labour 2017 · Cochrane Headline outcomes only
RR 0.91 [0.51, 1.62]
3 studies · 687 participants
Low

Remifentanil (PCA) vs epidural/CSE

Low Apgar score · women in labour with planned vaginal delivery

Remifentanil (PCA) showed no clear difference in apgar score ≤ 7 (< 7) at 5 min compared with epidural/CSE (low certainty).

1 finding from 1 review

Patient‐controlled analgesia with remifentanil versus alternative parenteral methods for pain management in labour 2017 · Cochrane Headline outcomes only
RR 1.26 [0.62, 2.57]
5 studies · 1322 participants
Low